BOC-PHE-ONP
- CAS No.
- 7535-56-0
- Chemical Name:
- BOC-PHE-ONP
- Synonyms
- BOC-PHE-ONP;Boc-L-Phe-ONp;BOC-PHENYLALANINE-ONP;BOC-PHE-ONP USP/EP/BP;Boc-Phe-(4-Nitrophenyl)OH;(Tert-Butoxy)Carbonyl Phe-ONp;Boc-L-phenylanine-4-nitropheny ester;BOC-L-PHENYLALANINE P-NITROPHENYL ESTER;BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER;N-Boc-L-Phenylalanine 4-nitrophenyl ester
- CBNumber:
- CB2150048
- Molecular Formula:
- C20H22N2O6
- Molecular Weight:
- 386.4
- MDL Number:
- MFCD00042811
- MOL File:
- 7535-56-0.mol
| Melting point | 127-128 °C |
|---|---|
| Boiling point | 558.4±50.0 °C(Predicted) |
| Density | 1.240±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| pka | 10.83±0.46(Predicted) |
| form | Crystalline Powder |
| color | White |
| Sensitive | Moisture Sensitive |
| CAS DataBase Reference | 7535-56-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-21 | |||||||||
| NFPA 704 |
|
BOC-PHE-ONP price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B662045 | Boc-Phe-ONP | 7535-56-0 | 50mg | $45 | 2021-12-16 | Buy |
| Usbiological | 264826 | Boc-L-phenylalanine 4-nitrophenyl ester | 7535-56-0 | 25g | $383 | 2021-12-16 | Buy |
| Matrix Scientific | 093193 | Boc-Phe-ONp 95+% | 7535-56-0 | 5g | $404 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AAA0003689 | BOC-PHE-ONP 95.00% | 7535-56-0 | 5G | $458 | 2021-12-16 | Buy |
| Matrix Scientific | 093193 | Boc-Phe-ONp 95+% | 7535-56-0 | 10g | $599 | 2021-12-16 | Buy |
BOC-PHE-ONP Chemical Properties,Uses,Production
Uses
4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate is a phenylalanine derivative[1].
Synthesis
100-02-7
13734-34-4
7535-56-0
The general procedure for the synthesis of Boc-L-aniline-4-nitrophenyl ester from 4-nitrophenol and Boc-L-phenylalanine is as follows: dissolve N-tert-butoxycarbonyl-L-phenylalanine (50 g) in dichloromethane (800 ml), stirring until completely dissolved. P-nitrophenol (39 g), 4-dimethylaminopyridine (DMAP, 3 g) and dicyclohexylcarbodiimide (DCC, 39 g) were added and the reaction was carried out for 5 hours at about 20°C. After completion of the reaction, the reaction mixture was filtered and the filtrate was evaporated. Ethanol was added to the residue and heated until complete dissolution, then slowly cooled to 20-30°C to allow the solid to precipitate gradually. Water (50 ml) was added and the mixture was cooled to 0°C and crystallized for 1 hour. The solid was collected by filtration to afford the target product Boc-L-aniline-4-nitrophenyl ester (62 g, 86.5% yield, 93% purity).
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-855. DOI:10.1080/10408398.2012.708368
BOC-PHE-ONP Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8617390183901 | cynthia@enlaibio.com | China | 1100 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 21569 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
View Lastest Price from BOC-PHE-ONP manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-18 | Boc-L-Phe-Onp
7535-56-0
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
 |
2020-01-15 | BOC-PHE-ONP
7535-56-0
|
US $1.00 / g | 100g | >98% | g/kg/Ton | Career Henan Chemical Co |
-
- Boc-L-Phe-Onp
7535-56-0
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- BOC-PHE-ONP
7535-56-0
- US $1.00 / g
- >98%
- Career Henan Chemical Co
