2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
- CAS No.
- 886497-81-0
- Chemical Name:
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
- Synonyms
- 2-Formyl-4-(trifluoromethoxy)fluorobenzene;2-Fluoro-5-(trifluoromethoxy)benzaldehyde97%;Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-;2-Fluoro-5-(trifluoromethoxy)benzaldehyde98%
- CBNumber:
- CB01119530
- Molecular Formula:
- C8H4F4O2
- Molecular Weight:
- 208.11
- MDL Number:
- MFCD04115886
- MOL File:
- 886497-81-0.mol
- MSDS File:
- SDS
| Boiling point | 200℃ |
|---|---|
| Density | 1.428 |
| Flash point | 73℃ |
| refractive index | 1.4430 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | liquid |
| color | Clear, colourless |
| Water Solubility | Slightly miscible with water. |
| Sensitive | Air Sensitive |
| CAS DataBase Reference | 886497-81-0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2913000090 | |||||||||
| NFPA 704 |
|
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | F599170 | 2-Fluoro-5-(trifluoromethoxy)benzaldehyde | 886497-81-0 | 50mg | $45 | 2021-12-16 | Buy |
| Apolloscientific | PC1092 | 2-Fluoro-5-(trifluoromethoxy)benzaldehyde 98% | 886497-81-0 | 1g | $35 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2615-3-42 | 2-Fluoro-5-(trifluoromethoxy)benzaldehyde 98% | 886497-81-0 | 1g | $39 | 2021-12-16 | Buy |
| Apolloscientific | PC1092 | 2-Fluoro-5-(trifluoromethoxy)benzaldehyde 98% | 886497-81-0 | 5g | $83 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2615-3-42 | 2-Fluoro-5-(trifluoromethoxy)benzaldehyde 98% | 886497-81-0 | 5G | $92 | 2021-12-16 | Buy |
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Chemical Properties,Uses,Production
Uses
2-Fluoro-5-(trifluoromethoxy)benzaldehyde is used as a precursor for organic synthesis. It is also used as a pharmaceutical intermediate.
Synthesis
352-67-0
68-12-2
886497-81-0
Example 49 3-Trifluoromethoxy-10-methyl-9H-imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine was synthesized as follows: a) Preparation of 2-fluoro-5-(trifluoromethoxy)benzaldehyde: 1-fluoro-4-(trifluoromethoxy)benzene (21.0 g, 117 mmol) was dissolved in tetrahydrofuran (THF, 233 mL) under dry conditions, and cooled to 4°C. A hexane solution of n-butyllithium (n-BuLi) was slowly added and the reaction temperature was kept below 10°C. The reaction mixture was ether The reaction mixture was extracted with ethyl ether and the organic phases were combined, washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. After concentration under reduced pressure, it was purified by silica gel column chromatography (eluent: heptane/ethyl acetate=100:0 to 80:2) to obtain 2-fluoro-5-(trifluoromethoxy)benzaldehyde (11.0 g, yield 53%) as a light yellow oil. 1H-NMR (300 MHz, DMSO-d6): δ=7.60 (t, J=9.2 Hz, 1H), 7.75-7.85 (m, 2H), 10.20 (s, 1H).
References
[1] Patent: US2006/128691, 2006, A1. Location in patent: Page/Page column 23-24
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12580 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
View Lastest Price from 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-12 | 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
886497-81-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-24 | 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
886497-81-0
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2019-07-11 | 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
886497-81-0
|
US $3.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
886497-81-0
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
886497-81-0
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
886497-81-0
- US $3.00 / KG
- 99%
- Career Henan Chemical Co
