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Granisetron Hydrochloride

Granisetron Hydrochloride Struktur
107007-99-8
CAS-Nr.
107007-99-8
Englisch Name:
Granisetron Hydrochloride
Synonyma:
GRANISETRON HYDROCHLORIDE;GRANISETRON HCL;KYTRIL;1-Methyl-N-[(1β,3α,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3-yl]-1H-indazole-3-carboxamide·hydrochloride;Kitryl;BRL-43694A;Gransetron HCl;GranisetronBase;midehydrochloride;GranisetronHclFda
CBNumber:
CB9728851
Summenformel:
C18H25ClN4O
Molgewicht:
348.87
MOL-Datei:
107007-99-8.mol

Granisetron Hydrochloride Eigenschaften

Schmelzpunkt:
290-292°C
storage temp. 
Room temp
L?slichkeit
H2O: >10mg/mL
Aggregatzustand
solid
Farbe
white to off-white
Merck 
14,4536
InChI
InChI=1/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12-,13+,14-;
InChIKey
QYZRTBKYBJRGJB-WQTKJZBYNA-N
SMILES
C12C=CC=CC=1N(C)N=C2C(=O)N[C@@H]1C[C@@]2([H])N(C)[C@]([H])(CCC2)C1.Cl |&1:13,15,19,r|
CAS Datenbank
107007-99-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,Xi
R-S?tze: 22-62-37/38-36/37/38-36
S-S?tze: 26-36-37-24/25
WGK Germany  3
RTECS-Nr. NK7882200
HS Code  29399990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit

Granisetron Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R62:Kann m?glicherweise die Fortpflanzungsf?higkeit beeintr?chtigen.
R37/38:Reizt die Atmungsorgane und die Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36:Reizt die Augen.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37:Geeignete Schutzhandschuhe tragen.

Beschreibung

Granisetron hydrochloride is the second selective 5HT-3-antagonist approved for the management of nausea and vomiting induced by cancer chemotherapy.Like ondansetron, granisetron hydrochloride is superior to metoclopramide in both efficacy and side effect profile. The compound appears to be effective both as a prophylactic agent and in blocking vomiting once started.

Chemische Eigenschaften

White to Off-White Crystalline Sold

Verwenden

A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemothera py. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarini c receptor

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biologische Aktivit?t

5-HT 3 receptor antagonist that possesses potent antiemetic activity.

Granisetron Hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Granisetron Hydrogenchlorid Methyljodid GRANISETRON IMPURITY B Natriumhydrid Propan-2-ol

Downstream Produkte

Granisetron Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 644)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
 xie@china-sinoway.com China 1000 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8617732866630
 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd 		+86-13288715578
sales@hbmojin.com China 12648 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208
 sales@aochuangchem.com China 9297 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971
deasea125996@gmail.com China 2472 58
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985
Amyjiyunzen@yeah.net China 664 58
Capot Chemical Co.,Ltd. 		+8613336195806
 sales@capot.com China 29731 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21622 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@
sales03@shyrchem.com CHINA 738 60

107007-99-8()Verwandte Suche:

  • 1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxamid
  • endo-1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxa
  • endo-monohydrochlorid
  • midehydrochloride
  • 1-METHYL-N-[(3-ENDO)-9-METHYL-9-AZABICYCLO[3.3.1]NON-3-YL]-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE
  • 1-Methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-isoindole-3-carboxamide hydrochloride
  • 1-Methyl-N-[(1β,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3α-yl]-1H-indazole-3-carboxamide·hydrochloride
  • Kitryl
  • Granisetron Hydrochloride, EP
  • Granisetron hydrochloride COS
  • Granisetron hydrochloride(BRL 43694)
  • Granisetron Hydrochloride (150 mg)
  • Granisetron dydrochloride
  • 1-methyl-N-(9-methyl-9-aza-bicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide hydrochloride
  • Granisetron hydrochloride 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride
  • 1-Methyl-N-((1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide hydrochl
  • BRL-43694A
  • GRANISERTROL HYDROCHLORIDE
  • GRANISTRON HYDROCHLORIDE
  • GranisetronHclFda
  • GranisetronBase
  • GranisetronHydrochlorideFdaInspected
  • Granisertronhydrochloride
  • Granisetron hydrocholride
  • BRL-43694A, Kytril, 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride
  • 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, monohydrochloride, endo-
  • 1H-Indazole-3-carboxamide, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, monohydrochloride
  • endo-monohydrochloride
  • Gransetron HCl
  • GRANISTERON HYDROCHLORIDE
  • 1-METHYL-N-(9-METHYL-9-AZABICYCLO[3.3.1]NON-3-YL)-INDAZOLE-3-CARBOXAMIDE HCL
  • 1-Methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-
  • 1-METHYL-1H-INDAZOLE-3-CARBOXYLIC ACID (9-METHYL-9-AZA-BICYCLO[3.3.1]NON-3-YL)-AMIDE: HYDROCHLORIDE
  • endo-1-Methyl-N-(9-methyl-9-azabicyclo[3．3．1]non-3-y1)-1H-indazole-3-carboxamide hydrochloride
  • Granisetron hydrochloride CRS
  • GranisetronHydrochloride>
  • 1-Methylindazole-3-carboxylic acid USP/EP/BP
  • Granisetron hydrochloride salt
  • Granisetron Hydrochloride/1-Methylindazole-3-carboxylic acid
  • Granisetron hydrochl
  • Granisetron HCl (BRL 43694A)
  • Granisetron HydrochlorideQ: What is Granisetron Hydrochloride Q: What is the CAS Number of Granisetron Hydrochloride Q: What is the storage condition of Granisetron Hydrochloride Q: What are the applications of Granisetron Hydrochloride
  • Granisetron Hydrochloride (1298106)
  • Granisetron hydrochloride, 98%, a serotonin 5-HT3 receptor antagonist
  • 1-Methyl-N-[(1β,3α,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3-yl]-1H-indazole-3-carboxamide·hydrochloride
  • KYTRIL
  • GRANISETRON HCL
  • GRANISETRON HYDROCHLORIDE
  • GranisetronHydrochloride/BRL43694A
  • Granisetron hydrochloride, 5-HT3 antagonist
  • rel-1-Methyl-N-((1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide hydrochloride
  • Granisetron hydrochloride, 10 mM in DMSO
  • GRANISETRON HYDROCHLORIDE USP
  • 107007-99-8
  • 156-2-21
  • C18H24N4OxHCl
  • C18H24N4OClH
  • C18H24N4OHClC18H25ClN4O
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