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Dolutegravir Impurity C

Dolutegravir Impurity C Struktur
1802141-49-6
CAS-Nr.
1802141-49-6
Englisch Name:
Dolutegravir Impurity C
Synonyma:
O-Ethyl Dolutegravir;Durutevir impurity 23;Dolutegravir Impurity 20;Dolutegravir Impurity 23;Dolutegravir Impurity 32;Syringaresinol Impurity 1(Syringaresinol Diglucoside);(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:;(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB96222324
Summenformel:
C22H23F2N3O5
Molgewicht:
447.43
MOL-Datei:
1802141-49-6.mol

Dolutegravir Impurity C Eigenschaften

Siedepunkt:
688.1±55.0 °C(Predicted)
Dichte
1.42±0.1 g/cm3(Predicted)
pka
10.71±0.40(Predicted)

Sicherheit

Dolutegravir Impurity C Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

O-Ethyl Dolutegravir is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity C Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dolutegravir Impurity C Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 10)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd. 020-89854820
sales@jzpharma.cn China 1300 58
Molcoo Chemicals Inc. 18576690171
 3001025734@qq.com China 9125 58
Shenzhen Roark Pharma-Tec Co., Ltd. 13128912434
 2880126944@qq.com China 2918 58
HX Pharmaceutical technology co., LTD 15671363360
 494267389@qq.com China 4557 58
guoyungurui 18162595016; 18162595016
 3287908757@qq.com China 10335 58
ShenZhen H&D Pharmaceutical Technology Co., LTD +86-13986652530 13986652530
 2850476883@qq.com China 7997 58
Hubei Moco Chemical Co., Ltd. 18627753421; 18627756402
 3001051413@qq.com China 19357 58
  • Dolutegravir Impurity 20
  • (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:
  • Dolutegravir Impurity 23
  • (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
  • Dolutegravir Impurity 32
  • Syringaresinol Impurity 1(Syringaresinol Diglucoside)
  • Durutevir impurity 23
  • O-Ethyl Dolutegravir
  • 1802141-49-6
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