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2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide

2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide Struktur
848688-62-0
CAS-Nr.
848688-62-0
Englisch Name:
2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide
Synonyma:
CAY10721;CAY10721,CAY-10721;2-(benzofuro[3,2-d]pyrimidin-4-ylthio)-N-(3-hydroxyphenyl)acetamide;Acetamide, 2-(benzofuro[3,2-d]pyrimidin-4-ylthio)-N-(3-hydroxyphenyl)-;2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide
CBNumber:
CB94593455
Summenformel:
C18H13N3O3S
Molgewicht:
351.37912
MOL-Datei:
848688-62-0.mol

2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide Eigenschaften

Siedepunkt:
651.8±55.0 °C(Predicted)
Dichte
1.50±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:4): 0.20 mg/ml
Aggregatzustand
A crystalline solid
pka
9.43±0.10(Predicted)

Sicherheit

2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy.

2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
 marketing@targetmol.com United States 32376 58
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 12952 65
BOC Sciences 16314854226
 info@bocsci.com United States 9923 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24983 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897
sales@caymanchem.com China 6838 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780
 sales@biosynth.com China 6051 58
Guangzhou Biopark Technology Co., Ltd. 020-83808789
CHINA 0 58
  • 2-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanyl)-N-(3-hydroxyphenyl)acetamide
  • CAY10721
  • CAY10721,CAY-10721
  • Acetamide, 2-(benzofuro[3,2-d]pyrimidin-4-ylthio)-N-(3-hydroxyphenyl)-
  • 2-(benzofuro[3,2-d]pyrimidin-4-ylthio)-N-(3-hydroxyphenyl)acetamide
  • 848688-62-0
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