Dinoprost, Trometamolsalz
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- CAS-Nr.
- 38562-01-5
- Bezeichnung:
- Dinoprost, Trometamolsalz
- Englisch Name:
- Dinoprost tromethamine
- Synonyma:
- 583e;u14585;lutalyse;Ensaprost;u-14,583e;PGF2ALPHA;PGF2αTris;Zinoprost;haminesalt;PGF2a-THAM
- CBNumber:
- CB9394313
- Summenformel:
- C24H45NO8
- Molgewicht:
- 475.62
- MOL-Datei:
- 38562-01-5.mol
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Dinoprost, Trometamolsalz Eigenschaften
- Schmelzpunkt:
- 100-101°
- storage temp.
- -20°C
- L?slichkeit
- H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.
- Aggregatzustand
- powder
- Farbe
- white
- Biologische Quelle
- synthetic
- Wasserl?slichkeit
- H2O: 1mg/mL
ethanol: 50mg/mL
- Merck
- 13,7970
- BRN
- 4087514
- Stabilit?t:
- Hygroscopic
- InChIKey
- IYGXEHDCSOYNKY-RZHHZEQLSA-N
- SMILES
- [C@@]1(C/C=C\CCCC(=O)O)([C@H](C[C@@H](O)[C@@]1(/C=C/[C@@H](O)CCCCC)[H])O)[H].C(N)(CO)(CO)CO |&1:0,10,12,14,17,r|
Dinoprost, Trometamolsalz Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R60:Kann die Fortpflanzungsf?higkeit beeintr?chtigen.
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
Dinoprost tromethamine is a synthetic analogue of prostaglandin. F2α is an autocrine hormone present in many mammalian tissues. It is used to cause luteolysis in the cow, sow and mare. It is given as a single injection by im or sc routes, the recommended dosage rate is 25 mg cow; 10 mg sow and 5 mg mare. It is rapidly absorbed from the injection site. It has an extremely short half life of only a few minutes, it is almost completely cleared following one or two passages through the liver and/or lungs.
Chemische Eigenschaften
White Solid
Indications
Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost tromethamine salt is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a key role in the onset and progression of labour.
Definition
dinoprost tromethamine is a synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum.
Sicherheitsprofil
Poison by intraperitoneal, subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Human reproductive effects by intervagmal route: terminates pregnancy, effects on fertility. Experimental teratogenic and reproductive effects. When heated to
decomposition it emits toxic fumes of NOx. See also other prostaglandin entries.
Dinoprost, Trometamolsalz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dinoprost, Trometamolsalz Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 294)Lieferanten
38562-01-5(Dinoprost, Trometamolsalz)Verwandte Suche:
- 583e
- 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicacid,tromet
- Tromethamine salt
- PGF2α (Prostaglandin F2α)
- Dinoprost TroMethaMine USP
- Dinorprost tromethamine
- (E,Z)-(1R,2R,3R,5S)-7-[3,5-Dihydroxy-2-[(3S)-(3-hydroxy-1-octenyl)]cyclopentyl]-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)@component of prostin F2 alpha, injectable
- Dinoprost compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Ensaprost
- Dinoprost Tromethamine (50 mg)
- (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid 2-AMino-2-(hydroxyMethyl)-1,3-propanediol
- 7-[3,5-Dihydroxy-2-(3-hydroxy-1-
octenyl)cyclopentyl]-5-heptenoic Acid TroMethaMine
- 9α,11α,15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid TroMethaMine
- 9α,11α-PGF2 TroMethaMine
- 9α,11α-PGF2α TroMethaMine
- thampgf2-alpha
- tromethamineprostaglandinf2-alpha
- u-14,583e
- u14585
- PROSTAGLANDINS F2ALPHA TRIS SALT
- PROSTAGLANDIN F2-ALPHA, TRIMETHAMINE SALT
- PROSTAGLANDIN F2ALPHA TRIS SALT
- PROSTAGLANDIN F2ALPHA TROMETHAMINE
- PROSTAGLANDIN F2ALPHA TROMETHAMINE SALT
- prostaglandin f2a tris salt
- PGF2ALPHA
- PGF2ALPHA THAM
- PGF2ALPHA-TRIS
- PGF2ALPHA TRIS SALT
- 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
- 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicacitham
- compd.withtrimethylolaminomethane
- haminesalt
- 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, TRIS(HYDROXYMETHYL) AMINOMETHANE SALT
- (5z,9a,11a,13e,15s)-9,11,15-trihydroxyprosta-5,13-dienoic acid tris salt
- Tromethamine prostaglandin F2α
- PGF2a-THAM
- PGF2α-Tris, Prostaglandin F2α tris salt, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt
- PGF2α-Tris, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt
- PGF2αTris
- lutalyse
- pgf2-alphatromethamine
- pgf2-alphatromethaminesalt
- prostaglandinf2-alphatham
- prostaglandinf2-alphathamsalt
- prostaglandinf2atromethamine
- protaglandinf2-alpha-thamsalt
- DINOPROST TROMETHAMINE
- DINOPROST (TROMETHAMINE SALT)
- dinoprost, trometamol salt
- prostaglandin F2A tris
- prostaglandin F2-alpha, trometamol salt
- PROSTAGLANDIN F2A TRIS GAMMA-IRRADIATED CELL CULTUR
- PROSTAGLANDIN F2A TRIS CELL*CULTURE TEST ED
- [5Z,9ALPHA,11ALPHA,13E,15S]-9,11,15-TRIHYDROXYPROSTA-5,13-DIENOIC ACID TRIS SALT
- Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9.alpha.,11.alpha.,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- (5z,9α,11α,13e,15s)-9,11,15-trihydroxyprosta-5,13-dienoic acid tris salt
- 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (5Z,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oate (salt) (9CI)
