2'-O-Methylcytidine
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2'-O-Methylcytidine Eigenschaften
- Schmelzpunkt:
- 252-253 C
- Siedepunkt:
- 506.0±60.0 °C(Predicted)
- Dichte
- 1.68±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- Soluble in DMSO.
- pka
- 13.37±0.70(Predicted)
- Aggregatzustand
- Powder
- Farbe
- White to Off-white
- PH
- 4.2
- Optische Rotation
- 70.902° (C=0.01 g/ml, H2O)
- maximale Wellenl?nge (λmax)
- 281 (pH 1);273 (EtOH)
- InChI
- InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
- InChIKey
- RFCQJGFZUQFYRF-ZOQUXTDFSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
- CAS Datenbank
- 2140-72-9(CAS DataBase Reference)
Sicherheit
Kennzeichnung gef?hrlicher | Xi | ||
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R-S?tze: | 36/37/38 | ||
S-S?tze: | 26-36-24/25 | ||
WGK Germany | 3 | ||
HS Code | 29349990 |
2'-O-Methylcytidine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).Chemische Eigenschaften
White powderVerwenden
2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.2'-O-Methylcytidine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2'-O-Methylcytidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 279)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 |
yunbiochem@126.com | China | 321 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43340 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20202 | 58 |
Capot Chemical Co.,Ltd. | +8613336195806 |
sales@capot.com | China | 29731 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29855 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10406 | 58 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 |
sales@unisyn.cn | CHINA | 332 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19552 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
2140-72-9()Verwandte Suche:
(Trifluormethoxy)benzol
Anisol
Methoxyessigs?ure
p-Anissure
4-Methoxy-anilin
Anisaldehyd
Methoxydiethylborane
POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE
5-Methylcytidin
2'-Desoxy-5-methylcytidin
2'-Desoxy-5-methylcytidin-5'-monophosphat
- 2'-OMe-C
- 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one
- 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
- 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one
- 2'-OMe Cytidine
- 4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one
- 2'-O-Methylcytidine, >=99%
- 2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
- 2'-O-Methylcytidineanhydrous
- 2'-O-Methyl-D-cytidine
- 2'-O-Methylcytidine, >98.0%(HPLC)
- 2'-O-Methylcytidine>
- 2'-OMe-rC
- 2'-O-Methylcytidine USP/EP/BP
- 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one
- 2'-OMe-Cr
- 2’-O-Methyl cytidine, RNA nucleoside Cm
- 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
- OMe-rC
- 2'-O-Methylcytidine
- 2'-OMe-cytidine
- 2'-O-Me-dC
- 2'-O-Me-rC
- Cytidine, 2'-O-methyl-
- 2'-O-Methyl-d3 Cytidine
- 2'-Methoxycytidine
- 2′-0-Methylcytidine
- 2'-O-Methylcytidine
- 2′-O-Methylcytidine - [M84857]
- 2140-72-9
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