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(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Struktur
419563-23-8
CAS-Nr.
419563-23-8
Englisch Name:
(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
Synonyma:
Peramivir Intermediater 2;(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate;methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate - [D86728];Methyl (1R,4S)-4-Amino-2-cyclopentenecarboxylate (2S,3S)-2,3-Dihydroxysuccinate;(2S,3S)-2,3-Dihydroxybutanedioic acid methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate;Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid
CBNumber:
CB93137449
Summenformel:
C11H17NO8
Molgewicht:
291.26
MOL-Datei:
419563-23-8.mol

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Eigenschaften

storage temp. 
2-8°C, protect from light
Aussehen
White to off-white Solid

Sicherheit

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658
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Jinan elephant international trading co., LTD
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Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725
 malulu@leyan.com China 54999 58
Nanjing Xiuhe Pharmaceutical Technology Co., Ltd. 19848384152
 2643971943@qq.com China 393 58
Pushan Industry (Shaanxi) Co., Ltd. 029-81310890 13571859809
 info@pushanshiye.com China 9909 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 18013972705
 qqyang@aikonchem.com China 10151 58
  • (1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
  • Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid
  • (2S,3S)-2,3-Dihydroxybutanedioic acid methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate
  • Peramivir Intermediater 2
  • Methyl (1R,4S)-4-Amino-2-cyclopentenecarboxylate (2S,3S)-2,3-Dihydroxysuccinate
  • methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate - [D86728]
  • 419563-23-8
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