trans-4-Dimethylaminocrotonic acid hydrochloride
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- CAS-Nr.
- 848133-35-7
- Englisch Name:
- trans-4-Dimethylaminocrotonic acid hydrochloride
- Synonyma:
- (E)-4-(dimethylamino)but-2-enoic acid hydrochloride;(e)-4-(dimethylamino)-2-butenoic acid hydrochloride;THRX-196194;Afatinib intermediate E;trans-4-Dimethylaminocrotonic;(E)-4-(Dimethylamino)-2-buteno;TRANS-4-DIMETHYLAMINOCROTONIC ACID HCL;4-DiMethylaMino-But-2-Enoic Acid Hcl Salt;(E)-4-(DIMETHYLAMINO)BUT-2-ENOIC ACID HCL;(2E)-4-(Dimethylamino)but-2-enoic acid HCl
- CBNumber:
- CB8854829
- Summenformel:
- C6H12ClNO2
- Molgewicht:
- 165.62
- MOL-Datei:
- 848133-35-7.mol
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trans-4-Dimethylaminocrotonic acid hydrochloride Eigenschaften
- Schmelzpunkt:
- 162 °C
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChI
- InChI=1S/C6H11NO2.ClH/c1-7(2)5-3-4-6(8)9;/h3-4H,5H2,1-2H3,(H,8,9);1H/b4-3+;
- InChIKey
- UUHNQHFOIVLAQX-BJILWQEISA-N
- SMILES
- C(/CN(C)C)=C\C(=O)O.Cl
- CAS Datenbank
- 848133-35-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitssch?dlich bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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trans-4-Dimethylaminocrotonic acid hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
trans-4-Dimethylaminocrotonic acid hydrochloride is a very important pharmaceutical intermediate and is an essential part of the structure of the anti-tumour drugs afatinib and neratinib. It is also an important organic synthesis reagent for the preparation of novel pyrazole derivatives and 6-heterocycloalkyl quinazoline derivatives.
Chemische Eigenschaften
White Solid
Verwenden
trans 4-Dimethylaminocrotonic acid HCl is a reagent used in the preparation of tyrosine kinase inhibiting antitumor agents.
trans-4-Dimethylaminocrotonic acid hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
trans-4-Dimethylaminocrotonic acid hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 385)Lieferanten
848133-35-7()Verwandte Suche:
- 2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride
- Afatinib int-2 Trans-4-Dimethylaminocrotonic acid hydrochloride
- 2-Butenoic acid, 4-(dimethylamino)-, (2E)-, hydrochloride
- trans-4-Dimethylaminocrotonic acid hydrochloride, >=97%
- trans-4-Dimethylaminocrotonic
- trans-4-dimethylaminocrotonic acid hydrochloride salt
- 4-DiMethylaMino-But-2-Enoic Acid Hcl Salt
- trans-4-Dimethylaminocrotonic acid hydrochloride
- TRANS-4-DIMETHYLAMINOCROTONIC ACID HCL
- 2-BUTENOIC ACID, 4-(DIMETHYLAMINO)-, HYDROCHLORIDE
- Afatinib intermediate E
- (2E)-4-(diMethylaMino)but-2-enoic acid hydrochloride
- trans-4-(DiMethylaMino)-2-butenoic Acid Hydrochloride
- trans-4-Dimethylaminocrotonic acid hydrochloride (E)-4-(Dimethylamino)-2-butenoic acid hydrochloride
- 2-Butenoic acid,4-(dimethylamino)-, hydrochloride (1:1), (2E)-
- trans-4-Dimethylaminocrotonic acid hydrochloride(848133-35-7)
- (E)-4-(DIMETHYLAMINO)BUT-2-ENOIC ACID HCL
- (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride, trans
- 2-Butenoic acid, 4-(dimethylamino)-, hydrochloride (1:1)
- (2E)-4-(Dimethylamino)but-2-enoic acid?hydrochloride (1:1)
- (E)-4-Dimethylaminocrotonic Acid Hydrochloride
- trans-4-Dimethylaminocrotonic acid hydrochloride ISO 9001：2015 REACH
- (e)-4-(dimethylamino)-2-butenoic acid hydrochloride
- (E)-4-(dimethylamino)but-2-enoic acid hydrochloride
- THRX-196194
- (E)-4-(Dimethylamino)-2-buteno
- (2E)-4-(dimethylamino)-2-Butenoic acid hydrochloride (1:1)
- (2E)-4-(Dimethylamino)but-2-enoic acid HCl
- trans-4-Dimethylaminocrotonic acid hydrochloride，(E)-4-(Dimethylamino)But-2-Enoic Acid Hydrochloride
- 848133-35-7Trans-4-dimethylaminocrotonicacidhydrochloride
- trans-4-Dimethylaminocrotonic acid HCl 98%
- 848133-35-7
- Others chemical reagents
- Amines
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 848133-35-7
