2'-O-MOE-A(Bz)-3'-phosphoramidite
|
|
|
- CAS-Nr.
- 251647-53-7
- Englisch Name:
- 2'-O-MOE-A(Bz)-3'-phosphoramidite
- Synonyma:
- DMT-2'-O-MOE-A(Bz)-CE;2’-MOE-dA(Bz) Amidite;2'-MOE-Bz-A Phosphoramidite;N6-Bz-5'-O-DMT-2'-O-MOE-A-CE;2'-O-MOE-Bz-A Phosphoramidite;2'-MOE-N-Bz Adenosine Amidite;2'-MOE-Bz-A CE Phosphoramidite;2'-O-MOE-rA(Bz)Phosphoramidite;2'-O-MOE-rA(Bz) Phosphoramidite);2'-O-MOE-A(Bz)-3'-phosphoramidite
- CBNumber:
- CB83051689
- Summenformel:
- C50H58N7O9P
- Molgewicht:
- 932.01
- MOL-Datei:
- 251647-53-7.mol
|
2'-O-MOE-A(Bz)-3'-phosphoramidite Eigenschaften
- storage temp.
- -20°C
- pka
- 7.87±0.43(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- InChIKey
- VPBYBQBHLYRLHG-VCCSSPGHNA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
2'-O-MOE-A(Bz)-3'-phosphoramidite Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
Chemische Eigenschaften
The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.
2'-O-MOE-A(Bz)-3'-phosphoramidite Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2'-O-MOE-A(Bz)-3'-phosphoramidite Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 128)Lieferanten
- 2'-O-MOE-A(Bz)-3'-phosphoramidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI)
- 2'-O-MOE-Bz-A Phosphoramidite
- N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
- 2'-O-MOE-A(Bz)-CE Phosphoramidite
- 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE
- DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite
- N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite
- Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite
- 2'-O-MOE-rA(Bz) Phosphoramidite)
- 5'-O-DMT-N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
- Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N6-benzoyl-adenosine -3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5'-DMTr-2'-MOE-N6-Bz-3'-CEP-Adenosine
- 5'-DMTr-2'-MOE-N6Bz-3'-O-CEP-ADENOSINE
- DMT-2′O-MOE-rA(bz) Phosphoramidite
- 2’-O-MOE-A(Bz)-3’-phospho ramidite, N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite
- N6-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)-adenosine-3’-CED-phosphoramidite
- N6-Bz-5'-O-DMT-2'-O-MOE-A-CE
- 5'-O-DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite
- 2'-MOE-Bz-A CE Phosphoramidite
- 5'-O-DMT-2'-O-MOE-N6-Benzoyl- Adenosine -3’-Cyanoethyl Phosphoramidite
- 2'-MOE-N-Bz Adenosine Amidite
- DMT-2'-O-MOE-A(Bz)-CE
- DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite
- 2’-MOE-dA(Bz) Amidite
- N6-Benzoyl-2-o-methyladenosine 3-ce phosphoramidite
- N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-O-(2-methoxyethyl)adenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
- 5'-ODMT-2'-OMOE-N-Bz Adenosine-3'-OCEPA
- DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite
- 2'-O-MOE-A(Bz)-CE-Phosphoramidite
- (2R,3R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- N6-Bz-2'-O-MOE-5'-O-DMT-A-3'-CE-Phosphoramidite
- 2'-O-MOE-rA(Bz)Phosphoramidite
- DMT-2'-O-MOE-rA(Bz) phosphoramidite
- 2'-MOE-Bz-A Phosphoramidite
- (2’-MOE-A) N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl
Phosphoramidite
- 5’-O-DMT-2’-
MOE-A(Bz)-
CE-
Phosphoramidite
- 251647-53-7
- C50H58N7O9P
- Amidite
