Anti-MFGE8 antibody produced in rabbit Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-MFGE8 antibody produced in rabbit has been used in immunofluorescence.
Allgemeine Beschreibung
MFGE8 (milk fat globule-EGF factor 8 protein) is a ~53kDa plasma membrane glycoprotein that is generated at the bud from the apical surface of mammary epithelial cells during lactation. It is composed of two specific functional domains: an N-terminal domain with two epidermal growth factor (EGF) repeats and a C-terminal domain with two Discoidin/F5/8C domains for binding of anionic phospholipids and/or extracellular matrices.
Biochem/physiol Actions
MFGE8 (milk fat globule-EGF factor 8) protein is involved in wide range of cellular interactions such as phagocytosis of apoptotic lymphocytes and other apoptotic cells, cell adhesion of sperm and the egg coat, intestinal mucosa repair, mammary gland branching morphogenesis, angiogenesis etc. It is potentially involved in different stages of sperm maturation and fertilization mechanism. It accelerates the engulfment of apoptotic carcinoma cells by living carcinoma cells which in turn promotes tumor growth.
Anti-MFGE8 antibody produced in rabbit Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
