raldh2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-ALDH1A2 antibody produced in rabbit has been used in:
- immunohistochemistry
- immunofluorescence
- western blotting
Allgemeine Beschreibung
Aldehyde dehydrogenase 1 family, member A2 (ALDH1a2) gene is mapped to human chromosome 15q21.3. It belongs to the aldehyde dehydrogenase (ALDH) family. The product of ALDH1a2 gene is the enzyme retinaldehyde dehydrogenase type 2. The protein is found in few adult tissues, mainly in the urogenital tract.
Biochem/physiol Actions
Aldehyde dehydrogenase 1 family, member A2 (ALDH1a2), also known as retinaldehyde dehydrogenase type II (RALDH2), catalyzes the synthesis of all trans-retinoic acid from vitamin A. ALDH1a2 acts as a tumor suppressor. It plays a vital role in early embryonic and cardiac development. Variation in the ALDH1a2 gene expression may increase the risk of developing congenital heart disease (CHD). Reduced levels of ALDH1a2 has been observed in human prostate cancer patients.
raldh2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
