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Talniflumate

Talniflumate Struktur
66898-62-2
CAS-Nr.
66898-62-2
Englisch Name:
Talniflumate
Synonyma:
somalgen;ba7602-06;TALNIFLUMATE;Talniflumate, >=99%;Talniflumate (BA 7602-06);TALNIFLUMATE(INTERMEDIATE);Talniflumate, 10 mM in DMSO;phthalidyl2-(3-trifluoromethylanilino)nicotinate;2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid phthalidyl ester;phthalidyl2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate
CBNumber:
CB7315594
Summenformel:
C21H13F3N2O4
Molgewicht:
414.33
MOL-Datei:
66898-62-2.mol

Talniflumate Eigenschaften

Schmelzpunkt:
165-167°C
Siedepunkt:
534.6±50.0 °C(Predicted)
Dichte
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
Chlorform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
2.72±0.10(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Pale Yellow
maximale Wellenl?nge (λmax)
287nm(CHCl3)(lit.)
Merck 
14,9044
Stabilit?t:
Acid Sensitive, Moisture Sensitive
InChI
InChI=1S/C21H13F3N2O4/c22-21(23,24)12-5-3-6-13(11-12)26-17-16(9-4-10-25-17)19(28)30-20-15-8-2-1-7-14(15)18(27)29-20/h1-11,20H,(H,25,26)
InChIKey
ANMLJLFWUCQGKZ-UHFFFAOYSA-N
SMILES
C1(NC2=CC=CC(C(F)(F)F)=C2)=NC=CC=C1C(OC1C2=C(C=CC=C2)C(=O)O1)=O

Sicherheit

RTECS-Nr. QT2999200
HS Code  2933.39.9200
Toxizit?t LD50 orally in rats: 12000 mg/kg (Los)

Talniflumate Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White to pale yellow crystalline powder

Verwenden

Talniflumate is a nonaspirin and nonsteroidal anti-inflammatory drug.

Biologische Aktivit?t

Calcium-activated chloride channel (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Possesses anti-inflammatory actions via inhibition of cyclooxygenases and inhibits Cl - /HCO 3 - exchanger activity. Increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.

Talniflumate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2-((3-(Trifluormethyl)phenyl)-amino)-3-pyridin-carbons?ure 3-Bromphthalid

Downstream Produkte

Talniflumate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 139)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
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 info@dycnchem.com China 52846 58
InvivoChem 		+1-708-310-1919 +1-13798911105
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Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763
 sales@tnjchem.com China 25356 58
TargetMol Chemicals Inc. 		+1-781-999-5354;
support@targetmol.com United States 38838 58

66898-62-2()Verwandte Suche:

  • 2-(alpha,alpha,alpha-trifluoro-m-toluidino)-nicotinicaciphthalidylester
  • 3-ftalidilicodelacido2-((3-(trifluormetil)fenil)amino)-3-piridincarboxilic
  • 3-phthalidylesterof2-((3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxyl
  • Talniflumate, >=99%
  • 2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinicacidphthalidylester
  • ba7602-06
  • phthalidyl2-(3-trifluoromethylanilino)nicotinate
  • phthalidyl2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate
  • somalgen
  • 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO]-3-PYRIDINECARBOXYLIC ACID 1,3-DIHYDRO-3-OXO-1-ISOBENZOFURANYL ESTER
  • 3-pyridinecarboxylic acid 2-{[(3-trifluoromethyl)phenyl]amino}-1,3-dihydro-3-oxo-1-soenzofuranyl ester
  • TALNIFLUMATE
  • TALNIFLUMATE(INTERMEDIATE)
  • 2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid phthalidyl ester
  • 2-[[3-(Trifluoromethyl)phenyl]amino]nicotinic acid 1,3-dihydro-3-oxoisobenzofuran-1-yl ester
  • 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl3-pyridinecarboxylicacidester
  • 2-[3-(trifluoromethyl)anilino]-3-pyridinecarboxylic acid (3-oxo-1H-isobenzofuran-1-yl) ester
  • (3-oxo-1H-2-benzofuran-1-yl) 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate
  • 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester
  • Talniflumate (BA 7602-06)
  • 3-Oxo-1,3-dihydroisobenzofuran-1-yl 2-((3-(trifluoromethyl)phenyl)amino)nicotinate
  • Talniflumate, 10 mM in DMSO
  • 66898-62-2
  • 66898-62
  • C21H13F3N2O4
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