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CDK2 INHIBITOR II

CDK2 INHIBITOR II Struktur
222035-13-4
CAS-Nr.
222035-13-4
Englisch Name:
CDK2 INHIBITOR II
Synonyma:
SC 221409;COMPOUND 3;CDK2 INHIBITOR II;CDK2-IN-3 (compound 3);SC 221409, Cdk2 inhibitor;4-(2-(5-Bromo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide;4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-benzenesulfonamide;Benzenesulfonamide, 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-
CBNumber:
CB7244623
Summenformel:
C14H11BrN4O3S
Molgewicht:
395.23
MOL-Datei:
222035-13-4.mol

CDK2 INHIBITOR II Eigenschaften

Schmelzpunkt:
>272°C (dec.)
Dichte
1.85±0.1 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly, Heated)
Aggregatzustand
Solid
pka
8.81±0.20(Predicted)
Farbe
Light Orange to Orange
InChI
InChI=1S/C14H11BrN4O3S/c15-8-1-6-12-11(7-8)13(14(20)17-12)19-18-9-2-4-10(5-3-9)23(16,21)22/h1-7,18H,(H2,16,21,22)(H,17,19,20)
InChIKey
ODZNNZYRBRRREX-UHFFFAOYSA-N
SMILES
C1(S(N)(=O)=O)=CC=C(NN=C2C3=C(NC2=O)C=CC(Br)=C3)C=C1

Sicherheit

CDK2 INHIBITOR II Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The cyclin-dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G2-M transition during the cell cycle. Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC50 = 60 nM). It is cell permeable, reversible, and ATP-competitive.

Verwenden

CDK2 inhibitor II, is a potent, cell-permeable, ATP-competitive, and selective inhibitor of Cdk2.

CDK2 INHIBITOR II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CDK2 INHIBITOR II Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 39)Lieferanten
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Aladdin Scientific
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Suzhou Su Taike Biological Reagent Co., Ltd. 18352410772
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J & K SCIENTIFIC LTD. 18210857532; 18210857532
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VDM Biochemicals 0330-2528181
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info@topbiochem.com China 9498 58
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8065 58
BOC Sciences 16314854226
 info@bocsci.com United States 9923 65
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123
 1014988033@qq.com China 4913 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
  • COMPOUND 3
  • CDK2 INHIBITOR II
  • SC 221409
  • Benzenesulfonamide, 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-
  • CDK2-IN-3 (compound 3)
  • 4-(2-(5-Bromo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide
  • 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-benzenesulfonamide
  • SC 221409, Cdk2 inhibitor
  • 222035-13-4
  • Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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