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Oxametacin

oxametacin  Struktur
27035-30-9
CAS-Nr.
27035-30-9
Bezeichnung:
Oxametacin
Englisch Name:
oxametacin
Synonyma:
Flogar;ABC-8/3;oxametacin;Oxametacine;oxamethacin;Indoxamic acid;1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid;1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide
CBNumber:
CB6939025
Summenformel:
C19H17ClN2O4
Molgewicht:
372.806
MOL-Datei:
27035-30-9.mol

Oxametacin Eigenschaften

Schmelzpunkt:
181-182° (dec)
Dichte
1.2671 (rough estimate)
Brechungsindex
1.6800 (estimate)
L?slichkeit
DMSO (Slightly), Methanol (Heated, Slightly)
Aggregatzustand
Solid
pka
9.00±0.20(Predicted)
Farbe
Crystals from dioxane

Sicherheit

Toxizit?t LD50 orally in rats: 96 mg/kg (De Martiis, U.S. patent)

Oxametacin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Oxametacine is prepared by the acylation of hydroxylamine with indomethacin acid chloride. Oxametacine at a dose of 100 mg is reported to be as effective as 50 mg of indomethacin in reducing pain and inflammation with a lower incidence of adverse effects.

Definition

ChEBI: A hydroxamic acid obtained by formal condensation of the carboxy group of indometacin with the amino group of hydroxylamine.

Sicherheitsprofil

Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When heated to decomposition it emits toxic fumes of Clí and NOx.

Oxametacin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Oxametacin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 11)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 32281 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19903 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 20614 58
Merck KGaA 21-20338288
ordercn@merckgroup.com China 6394 58
Santa Cruz Biotechnology Inc 60936350
scbt@scbt.com China 6068 58

27035-30-9(Oxametacin)Verwandte Suche:


  • 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide
  • 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid
  • 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid
  • ABC-8/3
  • Flogar
  • Indoxamic acid
  • oxametacin
  • oxamethacin
  • Oxametacine
  • 1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-
  • 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxyacetamide
  • 27035-30-9
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