ANTI-CASPASE-3
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- CAS-Nr.
- Englisch Name:
- ANTI-CASPASE-3
- Synonyma:
- ANTI-LICE;ANTI-YAMA;Anti-SCA1;ANTI-CASP3;ANTI-CPP32;ANTI-ICE-3;Anti-CPP32B;ANTI-APOPAIN;ANTI-CASPASE-3;ANTI-CPP32: HRPO
- CBNumber:
- CB6750242
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-CASPASE-3 Eigenschaften
- storage temp.
- −20°C
- Aggregatzustand
- lyophilized powder
- Biologische Quelle
- rabbit
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H312 |
Gesundheitssch?dlich bei Hautkontakt. |
Akute Toxizit?t dermal |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P280,P302+P352, P312, P322, P363,P501 |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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ANTI-CASPASE-3 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Caspase 3, Active antibody has been used:
- for western blotting of cytochrome c for caspase activation
- as primary antibody in immunofluorescence staining of embryos and postnatal mice cryosections
- in Western blot analysis of activated caspase 3
- as a primary antibody in immunodetection of rat brain sections
Allgemeine Beschreibung
Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3?is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3?is mapped to human chromosome 4q35.1.
Biochem/physiol Actions
Caspase 3 is one of the key effectors of apoptosis. It acts downstream of caspase 9 in the apoptotic pathway. During apoptosis, it gets activated by proteolytic cleavage into the 17-19 kDa (p17, p18) and 12 kDa (p12) active subunits. Any alteraion in CASP-3 in mice, causes premature lethality. It has also shown that the deletion of gene affects brain development resulting of hyperplasias and disorganized cell deployement. Clinically it is related to Huntington disease (HD). Caspase 3 brings about cell death by activating CAD (caspase activated DNAse I), an endonuclease that causes degradation of chromosomal DNA.
ANTI-CASPASE-3 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-CASPASE-3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 48)Lieferanten
- MONOCLONAL ANTIBODY TO CASPASE-3 (HUMAN) (31A1067)
- Anti-Caspase 3 antibody produced in rabbit
- Anti-Caspase 3, Active antibody produced in rabbit
- Monoclonal Anti-Caspase 3 antibody produced in mouse
- Anti-CASP3 antibody produced in rabbit
- Monoclonal Anti-CASP3 antibody produced in mouse
- CASPASE-3 (AB-2) MONOCLONAL ANTIBODY
- CASPASE-3 (AB-3) MONOCLONAL ANTIBODY
- CASPASE-3 (AB-4) MONOCLONAL ANTIBODY
- ANTI-APOPAIN (AB-2), HUMAN
- ANTI-APOPAIN (AB-2) MOUSE MAB
- ANTI-APOPAIN (AB-3), HUMAN
- ANTI-APOPAIN (AB-3) MOUSE MAB
- ANTI-APOPAIN (AB-4) MOUSE MAB
- ANTI-APOPAIN, ACTIVE RABBIT
- ANTI-APOPAIN (HUMAN)
- ANTI-APOPAIN, MOUSE
- ANTI-APOPAIN
- ANTI-APOPAIN (AB-1), HUMAN
- ANTI-CASPASE-3 (AB-2)
- ANTI-CASPASE-3 (AB-2), HUMAN
- ANTI-CASPASE-3 (AB-2) MOUSE MAB
- ANTI-CASPASE-3 (AB-3)
- ANTI-CASPASE-3 (AB-3), HUMAN
- ANTI-CASPASE-3 (AB-3) MOUSE MAB
- ANTI-CASPASE-3 (AB-4), HUMAN
- ANTI-CASPASE-3 (AB-4) MOUSE MAB
- ANTI-CASP3
- ANTI-CASP3 (AB-1), HUMAN
- ANTI-CASP3 (AB-2), HUMAN
- ANTI-CASP3 (AB-2) MOUSE MAB
- ANTI-CASP3 (AB-3), HUMAN
- ANTI-CASP3 (AB-3) MOUSE MAB
- ANTI-CASP3 (AB-4) MOUSE MAB
- ANTI-CASPASE-3 (HUMAN)
- ANTI-CASPASE-3, HUMAN (RABBIT)
- ANTI-CASPASE-3 RABBIT PAB
- ANTI-CASPASE 3, ACTIVE RABBIT
- ANTI-CPP32, MOUSE
- ANTI-CPP32, ACTIVE RABBIT
- ANTI-CPP32
- ANTI-CPP32 (AB-1), HUMAN
- ANTI-CPP32 (AB-2), HUMAN
- ANTI-CPP32(AB-2) MOUSE MAB
- ANTI-CPP32 (AB-3), HUMAN
- ANTI-CPP32 (AB-3) MOUSE MAB
- ANTI-CPP32 (AB-4) MOUSE MAB
- ANTI-CPP32, ACTIVE FORM
- ANTI-CASPASE 3 (CPP322)
- ANTI-CASPASE 3 (CPP32, APOPAIN, YAMA)
- ANTI-CASPASE-3(H-277)
- ANTI-CASPASE-3, ACTIVE FORM
- ANTI-CASPASE-3
- ANTI-CASPASE-3 (AB-1), HUMAN
- ANTI-CPP32: HRPO
- ANTI-CPP32 (HUMAN)
- ANTI-HUMAN CPP32
- ANTI-HUMAN CASPASE-3
