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MIF Antagonist, ISO-1

MIF Antagonist, ISO-1 Struktur
478336-92-4
CAS-Nr.
478336-92-4
Englisch Name:
MIF Antagonist, ISO-1
Synonyma:
ISO-1;CS-1195;ISO-1 (ISO 1;MIF Antagonist;ISO-1, 10 mM in DMSO;ISO-1, MIF Antagonist;MIF Antagonist, ISO-1;ISO 1;ISO1;MIF ANTAGONIST;ISO-1,Inhibitor,ISO1,inhibit;ISO 1, MIF-Antagonist, MIF antagonist
CBNumber:
CB62521242
Summenformel:
C12H13NO4
Molgewicht:
235.24
MOL-Datei:
478336-92-4.mol

MIF Antagonist, ISO-1 Eigenschaften

Schmelzpunkt:
114 °C
Siedepunkt:
365.0±48.0 °C(Predicted)
Dichte
1.30±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
L?slichkeit
Soluble in DMSO.
pka
9.22±0.30(Predicted)
Aggregatzustand
Light yellow crystalline solid.
Farbe
Off-white
Sensitive 
Light Sensitive
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChI
InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3
InChIKey
AIXMJTYHQHQJLU-UHFFFAOYSA-N
SMILES
O1C(CC(OC)=O)CC(C2=CC=C(O)C=C2)=N1

Sicherheit

MIF Antagonist, ISO-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

MIF Antagonist, ISO-1 inhibits MIF dopachrome tautomerase activity by binding to its catalytic active site (IC50 = 7 μM for D-dopachrome tautomerase) and suppresses the production of TNFα, PGE2 and COX-2 in human monocytes and arachidonic acid in RAW 264.7 macrophages. MIF Antagonist, ISO-1 has been shown to exhibit antidiabetogenic properties in immunoinflammatory diabetic mouse model.

MIF Antagonist, ISO-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MIF Antagonist, ISO-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 148)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32374 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040
 sales@myuchem.com China 8257 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471
sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 24727 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208
 sales@aochuangchem.com China 9297 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365
 mina@chuanghaibio.com China 18126 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38832 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58

478336-92-4()Verwandte Suche:

  • MIF Antagonist, ISO-1
  • Methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
  • ISO-1
  • MIF Antagonist
  • 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester
  • ISO-1 (ISO 1
  • ISO 1;ISO1;MIF ANTAGONIST
  • 5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester
  • 2-[3-(4-Hydroxyphenyl)-4,5-dihydroisoxazol-5-yl]acetic Acid Methyl Ester
  • CS-1195
  • ISO-1, MIF Antagonist
  • ISO-1,Inhibitor,ISO1,inhibit
  • ISO 1, MIF-Antagonist, MIF antagonist
  • ISO-1, 10 mM in DMSO
  • 478336-92-4
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