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LY3039478

LY3039478 Struktur
1421438-81-4
CAS-Nr.
1421438-81-4
Englisch Name:
LY3039478
Synonyma:
JSMD-194;LY3039478;Crenigacestat;LY3039478(Crenigacestat);CRENIGACESTAT (LY3039478);Crenigacestat, 10 mM in DMSO;Crenigacestat (LY3039478) ，S7169;LY3039478; LY 3039478; LY-3039478; CRENIGACESTAT;4-trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6;Inhibitor,γ-secretase,Crenigacestat,liver,LY 3039478,Notch,Gamma secretase,inhibit,LY-3039478,CCRCC
CBNumber:
CB52677403
Summenformel:
C22H23F3N4O4
Molgewicht:
464.44
MOL-Datei:
1421438-81-4.mol

LY3039478 Eigenschaften

Siedepunkt:
818.7±65.0 °C(Predicted)
Dichte
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≥23.2 mg/mL in DMSO; insoluble in H2O; ≥89.4 mg/mL in EtOH with ultrasonic
Aggregatzustand
solid
pka
12.75±0.20(Predicted)
Farbe
White to off-white

Sicherheit

LY3039478 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

LY 3039478 is used in the preparation of medicaments for combination antitumor therapy with Notch and PD-1 or PD-Li inhibitors.

LY3039478 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

(2S)-2-(4,4,4-trifluorobutanoylamino)propanoic acid 4,4,4-Trifluorobutyric acid (2S)-2-amino-N-[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]propanamide 6H-Pyrido[3,2-a][3]benzazepin-6-one, 7-amino-5,7-dihydro-5-(2-hydroxyethyl)-, (7S)- Propanamide, 2-?amino-?N-?[6,?7-?dihydro-?5-?(2-?hydroxyethyl)?-?6-?oxo-?5H-?pyrido[3,?2-?a]?[3]?benzazepin-?7-?yl]?-?, (2S)?- Dichlormethan N'-(Ethylkohlenstoffimidoyl)-N,N-dimethylpropan-1,3-diaminhydrochlorid 1-Hydroxybenzotriazol

Downstream Produkte

LY3039478 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 96)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32368 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471
sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38802 58
Aceschem Inc. 		+1-817863-6948 +1-（817）863-6948
 sales@aceschem.com United States 19632 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652
 info@fdachem.com China 20203 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
  • LY3039478
  • 4,4,4-Trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6,7-dihydro-5H-benzo[d]pyrido[2,3-b]azepin-7-yl)amino)-1-oxopropan-2-yl)butanamide
  • N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide
  • LY3039478(Crenigacestat)
  • CRENIGACESTAT (LY3039478)
  • Butanamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluoro-
  • Crenigacestat
  • LY3039478; LY 3039478; LY-3039478; CRENIGACESTAT
  • 4-trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6
  • Inhibitor,γ-secretase,Crenigacestat,liver,LY 3039478,Notch,Gamma secretase,inhibit,LY-3039478,CCRCC
  • Crenigacestat, 10 mM in DMSO
  • JSMD-194
  • Crenigacestat (LY3039478) ，S7169
  • 1421438-81-4
  • C22H23F3N4O4
  • APIS
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