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N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Struktur
179552-74-0
CAS-Nr.
179552-74-0
Englisch Name:
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
Synonyma:
Afatinib Impurity 137;Dacomitinib Intermediate 2;N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine;N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinam...;N - (3-Chloro-4-fluorophenyl) -7-methoxy-6-nitroquinoline-4-amine;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-;(3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine
CBNumber:
CB52629972
Summenformel:
C15H10ClFN4O3
Molgewicht:
348.72
MOL-Datei:
179552-74-0.mol

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Eigenschaften

Siedepunkt:
515.5±50.0 °C(Predicted)
Dichte
1.529±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
5.07±0.70(Predicted)

Sicherheit

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine hydrochloride Natriummethanolat Methanol 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

Downstream Produkte

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 119)Lieferanten
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  • N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
  • N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine
  • (3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine
  • 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-
  • Afatinib Impurity 137
  • N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinam...
  • N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
  • N - (3-Chloro-4-fluorophenyl) -7-methoxy-6-nitroquinoline-4-amine
  • Dacomitinib Intermediate 2
  • 179552-74-0
  • C15H10ClFN4O3
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