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Zongertinib

Zongertinib Struktur
2728667-27-2
CAS-Nr.
2728667-27-2
Englisch Name:
Zongertinib
Synonyma:
BI-1810631;Zongertinib;Zostertinib;BLU-451(LNG451);Toremifen citrate;Zostertinib BI-1810631;Zongertinib/BI 1810631;azol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-4-piperidinyl]-;N-[1-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxy-anilino]pyrimido[5,4-d]pyrimidin-6-yl]-4-piperidyl]prop-2-enamide;N-(1-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl)acrylamide
CBNumber:
CB512094450
Summenformel:
C29H29N9O2
Molgewicht:
535.6
MOL-Datei:
2728667-27-2.mol

Zongertinib Eigenschaften

Dichte
1.39±0.1 g/cm3(Predicted)
Aggregatzustand
Solid
pka
14.16±0.20(Predicted)
Farbe
Light yellow to green yellow
InChIKey
YSGNGFPNTLERCR-UHFFFAOYSA-N
SMILES
C(NC1CCN(C2=NC=C3N=CN=C(NC4=CC=C(OC5=CC=C6N(C)C=NC6=C5)C(C)=C4)C3=N2)CC1)(=O)C=C

Sicherheit

Zongertinib Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Zongertinib (also known as BI 1810631) is an investigational irreversible tyrosine kinase inhibitor (TKI) that selectively inhibits HER2 (ERBB2) while inhibiting epidermal growth factor receptor (EGFR), thereby limiting associated toxicity. This oral targeted therapy is being developed for the treatment of advanced non-small cell lung cancer (NSCLC) with HER2 (ERRB2) mutations.

Zongertinib Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Zongertinib Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 59)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
HangZhou RunYan Pharma Technology Co.,LTD. 		+8618882027439
 sales2@runyanpharma.com China 302 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196
 sale04@alfachem.cn China 12438 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471
sales@sarms4muscle.com China 10473 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658
 sales1@artkmedchem.com China 39003 58
Taizhou Creating Bio-pharm co., ltd. 		0576-88827176; +8613586099526
 post@creatingbiopharm.com China 218 58
Jinan Chuanbei Biotechnology Co., Ltd 18654547380; 15269175648
 qingyan7590@163.com China 22 58
Jinan Good Medical &Technology Ltd Co., +86-0086-531-55562571，18953105926 +86-13553167512
 935170726@qq.com China 52 58
Jinan shenlikang chemical technology co. LTD 0531-86092839 13153040268
 2425815073@qq.com China 264 58
CAREBIO PHARMA 18501057619
jackyfan@rebornpharma.com China 252 58
Suzhou Albertchem Co.,Ltd. 0512-88968486 18012631750
 sales@albertchemical.com China 287 58
  • 2-Propenamide, N-[1-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-4-piperidinyl]-
  • N-[1-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxy-anilino]pyrimido[5,4-d]pyrimidin-6-yl]-4-piperidyl]prop-2-enamide
  • Zongertinib
  • N-(1-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl)acrylamide
  • BI-1810631
  • Zongertinib/BI 1810631
  • BLU-451(LNG451)
  • Toremifen citrate
  • azol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-4-piperidinyl]-
  • Zostertinib
  • Zostertinib BI-1810631
  • N-{1-[8-({3-methyl-4-[(1-methyl-1H-1,3-benzodiazol-5-yl)oxy]phenyl}amino)-[1,3]diazino[5,4-d]pyrimidin-2-yl]piperidin-4-yl}prop-2-enamide
  • 2728667-27-2
  • C29H29N9O2
  • API
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