N-(tert-Butoxycarbonyl)-L-phenylalanin
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- CAS-Nr.
- 13734-34-4
- Bezeichnung:
- N-(tert-Butoxycarbonyl)-L-phenylalanin
- Englisch Name:
- N-(tert-Butoxycarbonyl)-L-phenylalanine
- Synonyma:
- BOC-PHE-OH;BOC-PHE;BOC-L-PHE-OH;BOC-L-PHE;BOC-L-PHENYLALANINE;N-BOC-L-PHENYLALANINE;BOC-PHENYLALANINE;L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-;BOC-ph-OH;BOC Phenly Alanine
- CBNumber:
- CB4781305
- Summenformel:
- C14H19NO4
- Molgewicht:
- 265.3
- MOL-Datei:
- 13734-34-4.mol
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N-(tert-Butoxycarbonyl)-L-phenylalanin Eigenschaften
- Schmelzpunkt:
- 85-87 °C(lit.)
- Siedepunkt:
- 408.52°C (rough estimate)
- Dichte
- 1.1356 (rough estimate)
- Brechungsindex
- 24.5 ° (C=1, EtOH)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone.
- Aggregatzustand
- Fine Crystalline Powder
- pka
- 3.88±0.10(Predicted)
- Farbe
- White
- Optische Rotation
- [α]20/D +25±1°, c = 1% in ethanol
- BRN
- 2219729
- InChI
- InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m0/s1
- InChIKey
- ZYJPUMXJBDHSIF-NSHDSACASA-N
- SMILES
- C(O)(=O)[C@H](CC1=CC=CC=C1)NC(OC(C)(C)C)=O
- CAS Datenbank
- 13734-34-4(CAS DataBase Reference)
- EPA chemische Informationen
- L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4)
N-(tert-Butoxycarbonyl)-L-phenylalanin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36:Reizt die Augen.
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S39:Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder
Verwenden
N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.
synthetische
Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).
N-(tert-Butoxycarbonyl)-L-phenylalanin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(tert-Butoxycarbonyl)-L-phenylalanin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 656)Lieferanten
13734-34-4(N-(tert-Butoxycarbonyl)-L-phenylalanin)Verwandte Suche:
- n-[(1,1-dimethylethoxy)carbonyl]-l-phenylalanin
- N-(tert-Butoxycarbonyl)-L-phenylalanine ,98.5%
- Boc-L-phenylalanine ,98%
- (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropionic acid
- (S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- N-(tert-Butyloxycarbonyl)-L-phenylalanine
- N-(tert-butoxycarbonyl)-L-phenylalaninal
- Boc-L-phenylalanine ,98.5%
- 2-BOC-AMINO-3-PHENYL-PROPIONIC ACID
- Boc-L-phenylalanine,N-(tert-Butoxycarbonyl)-L-phenylalanine
- L-PHENYLALANINE-N-T-BOC
- (S)-N-(tert-Butoxycarbonyl)phenylalanine
- tert-Butoxycarbonyl-L-phenylalanine
- N-Boc-L-phenylalanine
Boc-Phe-OH
- (2S)-2-{[(tert-butoxy)carbonyl]aMino}-3-phenylpropanoic acid
- Boc-Phe-OH >=99.0% (T)
- N-(tert-Butoxycarbonyl)-L-phenylalanine SynonyMs N-[(1,1-DiMethylethoxy)carbonyl]-L-phenylalanine
- Boc-L-phenylalanine≥ 99% (HPLC)
- BOC-L-Phenylalanine, 99+%
- BOC-L-Phenylalanine(Boc-Phe-OH)
- N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE(BOC-L-PHE-OH)
- 2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID
- N-Butoxycarbonyl-L-phenylalanine
- N-T-BOC-L-PHENYLALANINE FREE ACID
- N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE, 99+%
- BOC-L-PHENYLALANINE-OH
- Boc-Phe-OH (Boc-L-Phenylalanine)
- N-ALPHA-T-BUTYLOXYCARBONYL-L-PHENYLALANINE
- (2R)-3-phenyl-2-(tert-butoxycarbonylamino)propanoic acid
- BOC Phenly Alanine
- BOC-L-PHENYLALANINE extrapure
- N-(tert-Butoxycarbonyl)-L-phenylalanine, Boc-L-phenylalanine
- N-TERT-BUTYLOXYCARBONYL-DL-PHENYLALANINE
- N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE
- N-T-BOC-L-PHENYLALANINE
- N-T-BUTOXYCARBONYL-L-PHENYLALANINE
- N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanine
- N-ALPHA-TERT-BUTYLOXYCARBONYL-L-PHENYLALANINE
- N-ALPHA-T-BUTOXYCARBONYL-L-PHENYLALANINE
- N-ALPHA-T-BOC-L-PHENYLALANINE
- T-BUTYLOXYCARBONYL-L-PHENYLALANINE
- TBOC-L-PHENYLALANINE
- (S)-2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID
- RARECHEM AL BE 0755
- N-Boc-L-phenylalanine,99%e.e.
- Tert-Butoxycarbonyl L-Phenylalanine (BOC-L Phenylalanine)
- (Tert-Butoxy)Carbonyl Phe-OH
- (2S-2-[(2-MethylpropaN-2-Yloxycarbonylamino]-3-Phenylpropanoic Acid
- N-(tert-Butoxycarbonyl)-L-phenylalanine >
- BOC-ph-OH
- N-(tert-Butoxycarbonyl)-L-phenylalanine USP/EP/BP
- BOC-L-Phenylalanine (Bortezomib Impurity)
- N-(tert-Butoxycarbonyl)-L-phenylalanine,13734-34-4
- L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- BOC-PHE-OH
- BOC-PHENYLALANINE
- BOC-PHE
- BOC-L-PHE
