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MMPIP (hydrochloride)

MMPIP (hydrochloride) Struktur
1215566-78-1
CAS-Nr.
1215566-78-1
Englisch Name:
MMPIP (hydrochloride)
Synonyma:
242084;CS-2104;CS-1472;SB-242084 HCl;MMPIP hydrochloride, 10 mM in DMSO;MMPIP hydrochloride (479077-02-6 Free base);6-(4-Methoxyphenyl)-5-methyl-3-(pyridin-4-yl)isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride;6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide;MMPIP hydrochloride,MMPIP,system,nervous,neuropathic,behavior,pain,inhibit,central,glutamate,cognitive,allosteric,Metabotropic glutamate receptors,Inhibitor,metabotropic,mGluR,mGluR7
CBNumber:
CB43152692
Summenformel:
C19H16ClN3O3
Molgewicht:
369.802
MOL-Datei:
1215566-78-1.mol

MMPIP (hydrochloride) Eigenschaften

storage temp. 
Desiccate at RT
L?slichkeit
Soluble to 50 mM in DMSO
Aggregatzustand
Powder
Farbe
Light yellow to green yellow

Sicherheit

MMPIP (hydrochloride) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It does not affect other mGlu receptors. The modulation of mGluR7 by MMPIP is context dependent, in that it is not observed in all known mGluR7 signaling pathways. MMPIP has been used to investigate the role of mGluR7 in cocaine-mediated reward signaling, attention and impulse control, and cognitive behavior in mice and rats. MMPIP also reversibly inhibits constitutive activity of mGluR7 in sympathetic neurons from the rat superior cervical ganglion.

Verwenden

MMPIP Hydrochloride is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization.

MMPIP (hydrochloride) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MMPIP (hydrochloride) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32376 58
Bide Pharmatech Ltd. 400-164-7117 13681763483
product02@bidepharm.com China 42446 60
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772
huahero21@sina.com China 1774 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9803 58
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136
Sales@ATKchemical.com China 9823 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
lucy@atkchemical.com China 10014 58
Medi-tech Bioscientific Co., Ltd. 0519-83246372 13585352506
China 1844 58
Cckinase, Inc. +1 (732)236-3202
sales@cckinase.com United States 2738 58
Absin Bioscience Inc. 021-38015121 18438616290
wulan@absin.cn China 24731 58

  • 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
  • 242084
  • CS-1472
  • CS-2104
  • SB-242084 HCl
  • MMPIP hydrochloride (479077-02-6 Free base)
  • MMPIP hydrochloride,MMPIP,system,nervous,neuropathic,behavior,pain,inhibit,central,glutamate,cognitive,allosteric,Metabotropic glutamate receptors,Inhibitor,metabotropic,mGluR,mGluR7
  • MMPIP hydrochloride, 10 mM in DMSO
  • 6-(4-Methoxyphenyl)-5-methyl-3-(pyridin-4-yl)isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride
  • 1215566-78-1
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