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N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride

N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride Struktur
926023-82-7
CAS-Nr.
926023-82-7
Englisch Name:
N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride
Synonyma:
AMTB;AMTB HCl;AMTB NEW;AMTB hydrate;AMTB hydrochloride;AMTB hydrochloride, 10 mM in DMSO;N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(thiophen-2-ylmethyl)benzamide;N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride;N-(3-Aminopropyl)-2-((3-methylbenzyl)oxy)-N-(thiophen-2-ylmethyl)benzamide hydrochloride;N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)-benzamide hydrochloride (1:1) hyclate
CBNumber:
CB42518976
Summenformel:
C23H26N2O2S.HCl
Molgewicht:
431
MOL-Datei:
926023-82-7.mol

N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride Eigenschaften

storage temp. 
Desiccate at +4°C
L?slichkeit
DMSO: ≥10mg/mL
Aggregatzustand
powder
Farbe
white to tan
InChI
InChI=1S/C23H26N2O2S.ClH/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20;/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3;1H
InChIKey
UDXGBANGPYONOK-UHFFFAOYSA-N
SMILES
C(C1C=CC=CC=1OCC1C=CC=C(C)C=1)(=O)N(CCCN)CC1SC=CC=1.Cl

Sicherheit

WGK Germany  3

N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

AMTB hydrate has been used as an inhibitor of transient receptor potential cation channel, subfamily melastatin, member 8 (TRPM8) in breast cancer cells and murine T cells.

Biochem/physiol Actions

AMTB is a 2-benzyloxy-benzoic acid amide derivative, which also inhibits voltage-gated sodium channels (Nav) and their isoforms.

N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 67)Lieferanten
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EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
  • AMTB hydrate
  • N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)-benzamide hydrochloride (1:1) hyclate
  • AMTB hydrochloride
  • N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride
  • AMTB
  • AMTB NEW
  • AMTB HCl
  • voltage,channel,TRP Channel,inhibit,painful,breast,cancer,bladder,Inhibitor,sodium,AMTB hydrochloride,NaV,TRPM8,overactive,Transient receptor potential channels,gated,syndrome,cells
  • AMTB hydrochloride, 10 mM in DMSO
  • N-(3-Aminopropyl)-2-((3-methylbenzyl)oxy)-N-(thiophen-2-ylmethyl)benzamide hydrochloride
  • N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(thiophen-2-ylmethyl)benzamide
  • 926023-82-7
  • C23H26N2O2SHCl
  • C23H26N2O2SClH
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