(1S)-(+)-(Camphorylsulfonyl)oxaziridine
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- CAS-Nr.
- 104322-63-6
- Englisch Name:
- (1S)-(+)-(Camphorylsulfonyl)oxaziridine
- Synonyma:
- CAS:104322-63-6;(S)-(+)-(Camphorsulfonyl)Oxazi;(+)-(Camphorsulfonyl)oxaziridine;S-(10-Camphorsulfonyl)oxaziridine;(S)-(+)-(CAMPHORSULFONYL)OXAZIRIDINE;(S)-2,N-EPOXY-EXO-10,2-BORNANESULTAM;(+)-((CAMPHORYL)SULFONYL)OXAZIRIDINE;(S)-(+)-(Camphorylsulfonyl)oxaziridine;(1S)-(+)-(CAMPHORYLSULFONYL)OXAZIRIDINE;(1S)-(+)-(10-CAMPHORSULFONYL) OXAZIRINE
- CBNumber:
- CB3447891
- Summenformel:
- C10H15NO3S
- Molgewicht:
- 229.3
- MOL-Datei:
- 104322-63-6.mol
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(1S)-(+)-(Camphorylsulfonyl)oxaziridine Eigenschaften
- Schmelzpunkt:
- 172-174 °C(lit.)
- alpha
- 45 º (c=2, chloroform)
- Siedepunkt:
- 317.6±25.0 °C(Predicted)
- Dichte
- 1.2486 (rough estimate)
- Brechungsindex
- 1.5060 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- Chloroform (Sparingly), Methanol (Slightly)
- pka
- -11.75±0.40(Predicted)
- Aggregatzustand
- Crystals or Crystalline Powder
- Farbe
- White
- Optische Rotation
- [α]28/D +45°, c = 2 in chloroform
- BRN
- 6274370
- InChI
- InChI=1/C10H15NO3S/c1-8(2)7-3-4-9(8)6-15(12,13)11-10(9,5-7)14-11/h7H,3-6H2,1-2H3/t7-,9-,10?,11?/s3
- InChIKey
- GBBJBUGPGFNISJ-SENRVMEJNA-N
- SMILES
- C123C[C@]4([H])CC[C@@]1(C4(C)C)CS(=O)(=O)N2O3 |&1:2,6,r|
- CAS Datenbank
- 104322-63-6(CAS DataBase Reference)
(1S)-(+)-(Camphorylsulfonyl)oxaziridine Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
(1S)-(+)-(Camphorylsulfonyl)oxaziridine is white crystall powder
Verwenden
(1S)-(+)-(Camphorylsulfonyl)oxaziridine is a useful synthetic intermediate. Used for asymmetric hydroxylation
Synthese
The enantiopure (1S)-(+)-(Camphorylsulfonyl)oxaziridine and (1R)-(-)-(10-Camphorsulfonyl)oxaziridine and [(8,8- dichlorocamphor)sulfonyl]oxaziridines (2) are commercially available. They can also be prepared on a large scale via the oxidation of corresponding camphorsulfonimines with buffered Potassium Monoperoxysulfate (Oxone) or buffered peracetic acid. Since oxidation takes place from the endo face of the C=N double bond, only a single oxaziridine isomer is obtained. The precursor camphorsulfonimines can be prepared in 3 steps (>80% yield) from inexpensive (+)- and (-)-10-Camphorsulfonic Acids. A variety of (camphorylsulfonyl)oxaziridine derivatives such as (2)-(4) are also readily available via the functionalization of the camphorsulfonimines followed by oxidation.
Einzelnachweise
1. Mergelsberg, I.; Gala, D.; Scherer, D.; DiBenedetto, D.; Tanner TL 1992, 33, 161.
2. Davis, F. A.; Kumar, A.; Chen, B.-C. JOC 1991, 56, 1143.
3. Chen, B.-C.; Weismiller, M. C.; Davis, F. A.; Boschelli, D.; Empfield, J. R.; Smith, III, A. B. T 1991, 47, 173.
(1S)-(+)-(Camphorylsulfonyl)oxaziridine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(1S)-(+)-(Camphorylsulfonyl)oxaziridine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 280)Lieferanten
104322-63-6()Verwandte Suche:
- (2R,8AS)-(+)-(CAMPHORYLSULFONYL)OXAZIRIDINE
- (1S)-(+)-2,N-EPOXY-EXO-10,2-BORNANESULTAM
- (IS)-(+)-(10-Camphorsulfonyl)oxaziridine
- S-(10-Camphorsulfonyl)oxaziridine
- (4aS,7R,8aS)-9,9-DiMethyltetrahydro-4H-4a,7-Methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide
- (+)-(2R,8aS)-10-(CaMphorylsulfonyl)oxaziridine
- (4aS,7R,8aS)-Tetrahydro-9,9-diMethyl-4H-4a,7-Methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-Dioxide
- (1S)-(+)-(Camphorylsulfonyl)oxaziridine, (1S)-(+)-2,N-Epoxy-exo-10,2-bornanesultam
- (1α,5β,7α)-10,10-Dimethyl-4,5-epoxy-3-thia-4-azatricyclo[5.2.1.01,5]decane3,3-dioxide
- (3aS)-9,9-Dimethyloctahydro-3aβ,6β-methano-1,7aα-epoxy-2,1-benzisothiazole 2,2-dioxide
- (4aS,7R,8aS)-5,6,7,8-Tetrahydro-9,9-dimethyl-4H-4a,7-methanooxazirino[3,2-i][2,1]benzoisothiazole 3,3-dioxide
- (4aS,7R,8aS)-9,9-Dimethyl-4H-4a,7-methanotetrahydrooxazirino[3,2-i][2,1]benzisothiazole 3,3-dioxide
- (8aS)-5,6,7,8-Tetrahydro-9,9-dimethyl-4H-4aβ,7β-methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-dioxide
- (+)-(2R,8aS)-(Camphorylsulfonyl)oxaziridine,98+%
- (4AS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo-[c][1,2]oxazireno[2,3-b]isothiazole 3,3-
- (1S)-(+)-(10-Camphorsulfonyl)oxaziridine
(1S)-(+)-(Camphorylsulfonyl)oxaziridine
- (S)-(+)-(Camphorylsulfonyl)oxaziridine
- (4AS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo-[c][1,2]oxazireno[2,3-b]isothiazole 3
- (1S)-(+)-(CAMPHORYLSULFONYL)OXAZIRIDINE
- (1S)-(+)-(10-CAMPHORSULFONYL)OXAZIRIDINE
- (1S)-(+)-(10-CAMPHORSULPHONYL)OXAZIRIDINE
- (S)-(+)-(CAMPHORSULFONYL)OXAZIRIDINE
- (S)-2,N-EPOXY-EXO-10,2-BORNANESULTAM
- (+)-((CAMPHORYL)SULFONYL)OXAZIRIDINE
- (1S)-(+)-(10-Camphorsulfonyl)oxaziridine (1S)-(+)-2,N-Epoxy-exo-10,2-bornanesultam
- (+)-(2R,8aS)-(Camphorylsulfonyl)oxaziridine, 99+% ee, 99+%
- (S)-(+)-(Camphorsulfonyl)Oxazi
- (1S)-(+)-(10-CAMPHORSULFONYL) OXAZIRINE
- (2R 8AS)-(+)-(CAMPHORYLSULFONYL)OXAZIRIDINE [ASYMMETRIC OXIDIZING GR]
- (2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent]
- (S)-(10-Camphorsulfonyl)oxaziridine,99%e.e.
- (+)-(2R, 8aS)-(Camphorylsulfonyl)oxaziridine, 99+%, (99+% e.e.)
- (1S)-(+)-(1-Camphorsulfonyl)oxaziridine
- (2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine[AsymmetricOxidizingReagent]>
- 4H-4a,7-Methanooxazirino[3,2-i][2,1]benzisothiazole, tetrahydro-9,9-dimethyl-, 3,3-dioxide, (4aS,7R,8aS)-
- CAS104322-63-6 (1S)-(+)-(Camphorylsulfonyl)oxaziridine
- (+)-(2R,8aS)-(Camphorylsulfonyl)oxaziridine
- (+)-(Camphorsulfonyl)oxaziridine
- (4aS,7S,8aS)-9,9-dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide
- (1S,8R)-11,11-dimethyl-5-oxa-3λ?-thia-4-azatetracyclo[6.2.1.0?,?.0?,?]undecane-3,3-dione
- (1S,8R)-11,11-dimethyl-5-oxa-3λ?-thia-4-azatetracyclo[6.2.1.01,?.0?,?]undecane-3,3-dione
- CAS:104322-63-6
- (1S)-(+)-(10-Camphorsulfonyl)oxaziridine
- (1S)-(+)-(10-Camphorsulfonyl)oxaziridine 98%
- 104322-63-6
- C10H15NO3S
- Hydroxylation
- Asymmetric Synthesis
- Sulfur Compounds (for Synthesis)
- Bicyclic Monoterpenes
- Oxidation
- Terpenes
- Chiral Catalysts, Ligands, and Reagents
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Chiral Reagents
- pharmacetical
- chiral
