TAIFd Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
Human IL-32α is one of approximately 6 splice variants of a gene cloned from the human lung carcinoma stable transfectant, A549-Rβ. IL-32α has been shown to induce IL-8, TNF-α, and MIP-2 production from human and mouse macrophage cell lines. It is up-regulated in activated T- and NK-cells, and IFN-g-treated epithelial cells. Human recombinant IL-32α produced in
E. coli is a 131 amino acid non-glycosylated polypeptide with a molecular mass of 14.9 kDa.
Biochem/physiol Actions
Interleukin-32 (IL-32) is a proinflammatory cytokine. It stimulates the generation of interleukin-6 and tumor necrosis factor-α. It also has a role in cell apoptosis and immune responses. IL32 has been associated with inflammatory diseases.
TAIFd Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
