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8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Struktur
298220-99-2
CAS-Nr.
298220-99-2
Englisch Name:
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyma:
11-Fluoro Desloratadine;11-Fluoro Desloratadine HCl;Desloratadine EP Impurity A;11-Fluoro Dihydrodesloratadine;Desloratadine Impurity 1/Desloratadine EP Impurity A;Desloratadine EP Impurity A（11-Fluoro Desloratadine）;Desloratadine EP Impurity A Desloratadine EP Impurity A;Desloratadine Impurity 1 (Desloratadine EP Impurity A Monomer);8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine;8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
CBNumber:
CB32622191
Summenformel:
C19H20ClFN2
Molgewicht:
330.83
MOL-Datei:
298220-99-2.mol

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Eigenschaften

Schmelzpunkt:
>192°C (dec.)
Siedepunkt:
426.9±45.0 °C(Predicted)
Dichte
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
10.16±0.10(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Pale Orange
InChI
InChI=1S/C19H20ClFN2/c20-16-5-6-17-14(12-16)4-3-13-2-1-9-23-18(13)19(17,21)15-7-10-22-11-8-15/h1-2,5-6,9,12,15,22H,3-4,7-8,10-11H2
InChIKey
UTRNCHWURQHTSN-UHFFFAOYSA-N
SMILES
C12C(F)(C3CCNCC3)C3=CC=C(Cl)C=C3CCC1=CC=CN=2

Sicherheit

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

11-Fluoro Desloratadine is a fluorine substituted benzocycloheptapyridine derivative with antihistaminic activity.

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 80)Lieferanten
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  • 11-Fluoro Desloratadine
  • 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • Desloratadine EP Impurity A
  • 4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b]pyridin-11-yl]piperidine
  • 8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
  • Desloratadine Impurity 1/Desloratadine EP Impurity A
  • 11-Fluoro Desloratadine HCl
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-
  • 8-chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 11-Fluoro Dihydrodesloratadine
  • Desloratadine Impurity 1 (Desloratadine EP Impurity A Monomer)
  • 8-Chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Desloratadine Impurity)
  • Desloratadine EP Impurity A Desloratadine EP Impurity A
  • Desloratadine EP Impurity A（11-Fluoro Desloratadine）
  • 298220-99-2
  • C19H20N2ClF
  • C19H20ClFN2
  • Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
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