Azelnidipine
|
|
|
- CAS-Nr.
- 123524-52-7
- Englisch Name:
- Azelnidipine
- Synonyma:
- CS-905;CS-499;RS-9054;Calblock;Azelpine;Azedipine;Azelidipine;Azenildipine;AZELNIDIPINE;AZELINIDIPINE
- CBNumber:
- CB1781980
- Summenformel:
- C33H34N4O6
- Molgewicht:
- 582.65
- MOL-Datei:
- 123524-52-7.mol
|
Azelnidipine Eigenschaften
- Schmelzpunkt:
- 120-126°C
- Siedepunkt:
- 709.3±60.0 °C(Predicted)
- Dichte
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- DMSO: >10mg/mL
- pka
- 7.89(at 25℃)
- Aggregatzustand
- powder
- Farbe
- Yellow
- Merck
- 14,907
- InChIKey
- ZKFQEACEUNWPMT-UHFFFAOYSA-N
- SMILES
- C1(N)NC(C)=C(C(OC(C)C)=O)C(C2=CC=CC([N+]([O-])=O)=C2)C=1C(OC1CN(C(C2=CC=CC=C2)C2=CC=CC=C2)C1)=O
- CAS Datenbank
- 123524-52-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
|
|
| R-S?tze: |
22-41 |
|
|
| S-S?tze: |
26-39 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
US7968332 |
|
|
| HS Code |
2933.79.1500 |
|
|
| Toxizit?t |
LD50 in female, male mice, female, male rats (mg/kg): 785, 979, 1267, 1971 orally |
|
|
| Bildanzeige (GHS) |
 
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H318 |
Verursacht schwere Augensch?den. |
Schwere Augensch?digung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
|
Azelnidipine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R41:Gefahr ernster Augensch?den.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Yellow Solid
Verwenden
Azelnidipine is a dihydropyridine calcium channel blocker with antihypertensice activity. Azelnidipine is used for treating ischemic heart disease and cardiac remodeling after myocardial infarction. S
tudies show that Azelnidipine ttreatment can reduce the risk of hyperglycemia induced metabolic disorders
Application
Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Acute administration of azelnidipine prevents a sudden drop of cardiac function after acute stress. Azelnidipine may have a protective role in inflammation associated with atherosclerosis.
Biologische Aktivit?t
Azelnidipine, a novel dihydropyridine derivative, is a L-type calcium channel blocker and antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.
Azelnidipine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Azelnidipine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 406)Lieferanten
123524-52-7()Verwandte Suche:
- AZELNIDIPINE
- 3-[1-(Diphenylmethyl)-3-azetidinyl]-5-(1-methylethyl-2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
- AzelnidipineC33H34N406
- AZELINIDIPINE
- AZELNIDIPINE(FORR&DONLY)
- CS-905, RS-9054, 2-Amino-1,4-dihydro-6-methyl-4-(3 nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester
- Azelidipine
- Azenildipine
- Calblock
- CS-905
- 2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(methylethyl) ester
- (±)-2-AMino-1,4-dihydro-6-Methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(DiphenylMethyl)-3-azetidinyl] 5-(1-Methylethyl) Ester
- Calblock 3-[1-(DiphenylMethyl)-3-azetidinyl] 5-isopropyl (±)-2-AMino-1,4-dihyd
- Azelnidipine (Crystalline forM α)
- 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-aMino-6-Methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- Azelnidipine, >=99%
- 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-
- Azelnidipine USP/EP
- 3,5-Pyridinedicarboxylic acid, 2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester
- Azelnidipine 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(methylethyl) ester
- RS-9054
- 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridi
- 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-[1-(diphenylmethyl)-3-azetidinyl] ester O5-propan-2-yl ester
- CS-499
- Azelnidipine Azelnidipine
- Azelnidipine >
- 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl Ester
- 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
- Azelnidipine USP/EP/BP
- Azelnidipine (UR12592, CS-905, CCRIS-8650)
- AzelnidipineQ: What is
Azelnidipine Q: What is the CAS Number of
Azelnidipine Q: What is the storage condition of
Azelnidipine Q: What are the applications of
Azelnidipine
- Fold the horizon
- Azedipine
- Azelnidipine Reference Standard
- Azelnidipine, ≥ 98.0%
- Azelnidipine powder
- Azelpine
- Azelnidipine, 10 mM in DMSO
- 123524-52-7
- 23524-52-7
- C33H34N4O6
- Inhibitors
- Cardiovascular Drugs
- API
