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ANTI-CDS1 (AB-1) (526-541) RABBIT PAB

ANTI-CDS1 (AB-1) (526-541) RABBIT PAB Struktur
CAS-Nr.
Englisch Name:
ANTI-CDS1 (AB-1) (526-541) RABBIT PAB
Synonyma:
ANTI-CHK2;ANTI-CSD1;Anti-CDB1;Anti-CDG2;ANTI-HCDS1;Anti-BIGH3;Anti-CDGG1;Anti-RAD53;Anti-PP1425;Anti-RGD-CAP
CBNumber:
CB1358151
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-CDS1 (AB-1) (526-541) RABBIT PAB Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution
Biologische Quelle
rabbit

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 22

ANTI-CDS1 (AB-1) (526-541) RABBIT PAB Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-TGFBI antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

TGFBI (transforming growth factor β induced) is a secretory protein, the secretion of which is induced by TGFβ in fibroblasts. It was first recognized in TGFβ-treated human lung adenocarcinoma cell line (A549). It is a highly conserved 68kDa protein, composed of 683 amino acids. It is predominantly expressed by fibroblasts, muscle cells and keratinocytes.

Biochem/physiol Actions

TGFBI (transforming growth factor β induced) in involved in the initiation of morphongensis, inflammation, cell division, adhesion, proliferation, migration and differentiation. It acts as linker protein mediating the interaction of integrin to ECM (extracellular matrix) proteins. It is up-regulated in multiple human cancers, such as colorectal cancer, where its expression is linked to poor prognosis. It acts as a regulator of cyclins and CDKs (cyclin dependent kinases) in melanomas, and is highly secreted by metastatic melanoma cell. Thus, it facilitates growth and survival in metastatic melanoma cells. In HBV (hepatitis B virus)-related HCC (hepatocellular carcinoma), the aberrant expression of this protein is linked to the oncogenic potential of HBV S gene.

ANTI-CDS1 (AB-1) (526-541) RABBIT PAB Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-CDS1 (AB-1) (526-541) RABBIT PAB Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 5)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Merck KGaA 21-20338288
ordercn@merckgroup.com China 6394 58

  • CHK2/HCDS1 (AB-1) POLYCLONAL ANTIBODY
  • Anti-TGFBI antibody produced in rabbit
  • Anti-TGFBI antibody produced in goat
  • ANTI-CDS1 (AB-1) (526-541) RABBIT PAB
  • ANTI-CDS1 (AB-1), HUMAN
  • ANTI-CHK2
  • ANTI-CHK2 (AB-1) (526-541) RABBIT PAB
  • ANTI-CHK2 (AB-1), HUMAN
  • ANTI-CHK2 (AB-2), HUMAN
  • ANTI-CHK2 (AB-2) MOUSE MAB
  • ANTI-CHK2/HCDS1 (AB-1) (526-541) RABBIT PAB
  • ANTI-CHK2/HCDS1 (AB-1), HUMAN
  • ANTI-CSD1
  • ANTI-CHK2 (AB-1)
  • ANTI-HCDS1
  • ANTI-HCDS1 (AB-1) (526-541) RABBIT PAB
  • ANTI-HCDS1 (AB-1), HUMAN
  • Anti-BIGH3
  • Anti-CDB1
  • Anti-CDGG1
  • Anti-transforming growth factor, beta-induced, 68kDa
  • Transforming growth factor, beta-induced, 68kDa
  • Anti-CDG2
  • Anti-Kerato-epithelin
  • Anti-RGD-CAP
  • Anti-Transforming growth factor-beta-induced protein ig-h3 precursor
  • Anti-Beta ig-h3
  • Anti-RGD-containing collagen-associated protein
  • Anti-PP1425
  • Anti-RAD53
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