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(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Struktur
874460-46-5
CAS-Nr.
874460-46-5
Englisch Name:
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride
Synonyma:
Aprepitant Impurity 3 HCl;Aprepitant Impurity 7 HCl;Aprepitant Impurity SM3QF;Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride;(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity)
CBNumber:
CB12669002
Summenformel:
C20H20ClF6NO2
Molgewicht:
455.83
MOL-Datei:
874460-46-5.mol

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Eigenschaften

Sicherheit

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1''S)-Aprepitant Hydrochloride is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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874460-46-5()Verwandte Suche:

  • (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride
  • Aprepitant Impurity 3 HCl
  • Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride
  • Aprepitant Impurity SM3QF
  • Aprepitant Impurity 7 HCl
  • (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity)
  • (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride
  • 874460-46-5
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