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garcinol

garcinol Struktur
78824-30-3
CAS-Nr.
78824-30-3
Englisch Name:
garcinol
Synonyma:
802;CP-54;garcinol;HSDB 7825;Camboginol;Garcinol, 10 mM in DMSO;Garcinol, HAT p300 and PCAF inhibitor;(1R,5R,7R)-3-(3,4-Dihydroxybenzyol)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione;(1R,5R,7R)-3-(3,4-Dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-Bicyclo[3.3.1]non-3-ene-2,9-dione;Bicyclo[3.3.1]non-3-ene-2,9-dione, 3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (1R,5R,7R)-
CBNumber:
CB11347121
Summenformel:
C38H50O6
Molgewicht:
602.8
MOL-Datei:
78824-30-3.mol

garcinol Eigenschaften

Schmelzpunkt:
132 °C
Siedepunkt:
710.8±60.0 °C(Predicted)
Dichte
1.114±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
pka
4.50±1.00(Predicted)
Aggregatzustand
Yellow solid.
Farbe
Yellow
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Garcinol is prone to oxidation. Protect from exposure to air.
LogP
11.546 (est)

Sicherheit

garcinol Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Garcinol is an inhibitor of the histone acetyltransferases (HATs) p300 and PCAF (IC50 = 7 and 5 μM, respectively). It also inhibits the HAT GCN5 in Cryptococcus neoformans, inducing temperature sensitivity and impairing growth. A polyisoprenylated benzophenone isolated from Garcinia indica, garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells. Moreover, it induces apoptosis in several types of cancer cells and has anti-inflammatory actions.

garcinol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


garcinol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 120)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29807 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 32283 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10244 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514
ada@ipurechemical.com CHINA 3461 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38665 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501
product@acmec-e.com China 33338 58
Aladdin Scientific

tp@aladdinsci.com United States 57505 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
AdooQ BioScience, LLC +1 (866) 930-6790
info@adooq.com United States 2782 58

78824-30-3()Verwandte Suche:


  • (1R,5R,7R)-3-(3,4-Dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-Bicyclo[3.3.1]non-3-ene-2,9-dione
  • Camboginol
  • (1R,3E,5R,7R)-3-[(3,4-dihydroxyphenyl)-hydroxy-methylidene]-8,8-dimethyl-1,7-bis(3-methylbut-2-enyl)-5-[(2S)-5-methyl-2-prop-1-en-2-yl-hex-4-enyl]bicyclo[3.3.1]nonane-2,4,9-trione
  • garcinol
  • (1R,5R,7R)-3-(3,4-Dihydroxybenzyol)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione
  • Bicyclo[3.3.1]non-3-ene-2,9-dione, 3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (1R,5R,7R)-
  • 802
  • CP-54
  • HSDB 7825
  • Garcinol, HAT p300 and PCAF inhibitor
  • Garcinol, 10 mM in DMSO
  • 78824-30-3
  • C38H50O6
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