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Clofexamid

clofexamide  Struktur
1223-36-5
CAS-Nr.
1223-36-5
Bezeichnung:
Clofexamid
Englisch Name:
clofexamide
Synonyma:
ANP246;NP-246;IEM-455;ANP 246;ANP-246;clofexamide;Chlofexamide;Amichlophene;2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide;Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]-
CBNumber:
CB0884312
Summenformel:
C14H21ClN2O2
Molgewicht:
284.78
MOL-Datei:
1223-36-5.mol

Clofexamid Eigenschaften

Schmelzpunkt:
45 °C
Siedepunkt:
124.5°C (rough estimate)
Dichte
1.1742 (rough estimate)
Brechungsindex
1.5200 (estimate)
pka
14.19±0.46(Predicted)

Sicherheit

Toxizit?t LD50 oral in rat: 1040mg/kg

Clofexamid Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Clofexamide ,CNRS

Manufacturing Process

In 1 L of water there is dissolved 116.0 g (1 mole) of N,Ndiethylethylenediamine and, under vigorous stirring at a temperature maintained below 50°C, there is added 205.0 g (1 mole) of the chloride of pchlorphenoxyacetic acid. The solution becomes rapidly homogeneous; the formation of the basic amide hydrochloride is rapidly completed by further stirring the reaction mixture for 2 h at about 20°C. Then an excess of soda lye is added and the basic amide formed is extracted by ether. The ethereal solution is dried on anhydrous sodium sulfate and ether is distilled after that the residue is dried. So 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl) acetamide is obtained.

Therapeutic Function

Antidepressant, Analgesic, Antiinflammatory, Local anesthetic

Clofexamid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Clofexamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 10)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32376 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30230 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19939 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739
info@dycnchem.com China 53900 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 029-029-81120477 17792793610
1033@dideu.com China 9829 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24982 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 18100677375
sales@szzxbio.com China 2978 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013
780229652@qq.com China 1274 58

1223-36-5(Clofexamid)Verwandte Suche:


  • clofexamide
  • 2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
  • Amichlophene
  • Chlofexamide
  • IEM-455
  • NP-246
  • ANP 246
  • ANP246
  • ANP-246
  • Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]-
  • 1223-36-5
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