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Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Struktur
58001-19-7
CAS-Nr.
58001-19-7
Englisch Name:
Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
Synonyma:
Isoergoline;Isonicergoline;Nicergoline EP Impurity F(RSS);N-Nitroso Betahistine Para Isomer;Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-;((6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate;(6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate (isonicergoline)
CBNumber:
CB08806413
Summenformel:
C24H26BrN3O3
Molgewicht:
484.39
MOL-Datei:
58001-19-7.mol

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Eigenschaften

Siedepunkt:
594.4±50.0 °C(Predicted)
Dichte
1.47±0.1 g/cm3(Predicted)
pka
6.33±0.40(Predicted)
InChIKey
YSEXMKHXIOCEJA-HWXJYTLHNA-N
SMILES
O([C@]12C[C@H](COC(C3=CN=CC(Br)=C3)=O)CN(C)[C@]1([H])CC1=CN(C)C3=CC=CC2=C13)C |&1:1,3,18,r|

Sicherheit

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

8-epi Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 32)Lieferanten
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Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
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Yangzhou Changhua Biotechnology Co., Ltd. 15189846850 13815846020
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  • Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
  • Isonicergoline
  • ((6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate
  • (6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate (isonicergoline)
  • Isoergoline
  • Nicergoline EP Impurity F(RSS)
  • N-Nitroso Betahistine Para Isomer
  • 58001-19-7
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