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2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Struktur
60762-57-4
CAS-Nr.
60762-57-4
Englisch Name:
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
Synonyma:
Pirlindol;Pyrazidol;Pirlindole;Pirlindolum;Unii-V39yph45fz;PIRLINDOLE MESYLATE;Pirlindole free base;Ombitasvir Impurity 6;Pirlindolum [inn-latin];16154-78-2 (Hydrochloride)
CBNumber:
CB0671512
Summenformel:
C15H18N2
Molgewicht:
226.32
MOL-Datei:
60762-57-4.mol

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Eigenschaften

storage temp. 
Store at RT
L?slichkeit
DMF: 1 mg/ml; DMSO: 5 mg/ml
Aggregatzustand
A crystalline solid
Farbe
Off-white to light yellow

Sicherheit

HazardClass  IRRITANT

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 μM independent of MAO-A activity.

Verwenden

Antidepressive;Monoamine oxidase inhibitor

Biologische Aktivit?t

A highly selective reversible inhibitor of monoamine oxidase type A.

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 48)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
 marketing@targetmol.com United States 32376 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 19939 58
Shaanxi Dideu New Materials Co. Ltd 		+86-18192503167
1036@dideu.com China 6395 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739
 info@dycnchem.com China 53900 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532
 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 12952 65
  • PIRLINDOLE MESYLATE
  • 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole
  • 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole
  • 16154-78-2 (Hydrochloride)
  • Pirlindol
  • Pirlindol [inn-spanish, french]
  • Pirlindolum
  • Pirlindolum [inn-latin]
  • Unii-V39yph45fz
  • Pirlindole
  • 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
  • 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole methanesulfonate
  • 1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl-
  • Pirlindole free base
  • Pyrazidol
  • Ombitasvir Impurity 6
  • 60762-57-4
  • C15H18N2CH3SO3H
  • Monoamine Oxidase
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