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Venlafaxine hydrochloride

Venlafaxine hydrochloride  Struktur
99300-78-4
CAS-Nr.
99300-78-4
Englisch Name:
Venlafaxine hydrochloride
Synonyma:
VENLAFAXINE HCL;EFFEXOR;D,L-VENLAFAXINE;D,L-VENLAFAXINE, HYDROCHLORIDE;Vexor;Venlift;AKOS 92111;VENLAFAXINEHCL;Venlaffaxine HCL;Venlafaxine HCL API
CBNumber:
CB0136181
Summenformel:
C17H28ClNO2
Molgewicht:
313.86
MOL-Datei:
99300-78-4.mol

Venlafaxine hydrochloride Eigenschaften

Schmelzpunkt:
207-209°C
Flammpunkt:
9℃
storage temp. 
2-8°C
L?slichkeit
H2O: >10mg/mL
Aggregatzustand
powder
Farbe
white
Wasserl?slichkeit
water: 100mM
DMSO: 50mM
Merck 
14,9946
BCS Class
1
InChI
InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChIKey
QYRYFNHXARDNFZ-UHFFFAOYSA-N
SMILES
OC1(CCCCC1)C(C1=CC=C(OC)C=C1)CN(C)C.[H]Cl
CAS Datenbank
99300-78-4(CAS DataBase Reference)
EPA chemische Informationen
Cyclohexanol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-, hydrochloride (1:1 (99300-78-4)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi,T,F
R-S?tze: 36/37/38-36-39/23/24/25-23/24/25-11
S-S?tze: 26-37/39-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS-Nr. GV8872760
HS Code  29225090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H411 Giftig für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 2
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P391 Verschüttete Mengen aufnehmen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Venlafaxine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Venlafaxine hydrochloride, a novel phenethylamine derivative, was introduced in the U.S.A. as an antidepressant. Venlafaxine is reported to be the first in the class of the second-generation of antidepressants with dual serotonidnorepinephrine reuptake inhibitory activity. Venlafaxine lacks any affinity for muscarinic, cholinergic, histaminergic and noradrenergic receptors and therefore, has an unusually favorable side effect profile compared with classical tricyclic antidepressants and shows less cardiotoxicity. In addition, venlafaxine has a rapid onset of action that makes it unique among the antidepressant agents. Other indications for venlafaxine include the treatment of obsessive and panic disorders, and obesity. Both enantiomers of venlafaxine were reported to have similar biological activity.

Chemische Eigenschaften

White Crystalline Powder

Verwenden

A selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant

Allgemeine Beschreibung

A Certified Snap-N-Spike? Solution suitable for many LC/MS and GC/MS applications from forensic or clinical toxicology analysis to urine drug testing. Also known by the brand name Effexor?, venlafaxine is an SNRI antidepressant approved for the treatment of major depressive and general anxiety disorders.

Biologische Aktivit?t

Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (K i values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.

Venlafaxine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Venlafaxine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 681)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8617732866630
abby@chuanghaibio.com China 8773 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677
faithe@yan-xi.com China 5853 58
Anhui Yiao New Material Technology Co., Ltd
+86-18033737140 +86-17354101231
sales1@hbganmiao.com China 227 58
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 973 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
+86-18600796368
sales@sjar-tech.com China 485 58
Wuhan JiyunZen Tech Co., Ltd.
+86-18062099985
Amyjiyunzen@yeah.net China 663 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3009 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763
info@tnjchem.com China 2988 55
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2930 58

99300-78-4()Verwandte Suche:


  • AKOS 92111
  • Effexor hydrochloride
  • Wy 45030 hydrochloride
  • (rs)-1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
  • VENLAFAXINE HYDROCHLORIDE
  • 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-cyclohexanohydrochloride
  • VENLAFAXINE HCI, 99%
  • VenlfaxineHydrochloride
  • Venlafaxinehydrochloride/VenlafaxineHCl
  • N,N-dimethyl-2-p-methoxyphenyl-2-(1-hydroxycyclohexyl) ethylamine hydrochloride
  • VENLAFAXINEHCL
  • 1-[2-DIMETHYL AMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANONE HYDROCHLORIDE (+)
  • Venlaffaxine HCL
  • Venlafaxine hydrochloride,(+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor
  • Venlafaxine Hydrochloride (100 mg)
  • Venlafaxine hydrochloride solution
  • 1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL, HCL
  • 1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL HYDROCHLORIDE
  • 1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL
  • (+/-)-1-(alpha-((dimethylamino)methyl)-p-methoxybenzyl)cyclohexanol hydrochloride
  • 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-1-cyclohexanol hydrochloride
  • Venlafaxine hydrochloride CRS
  • Venlafaxine hydrochloride solution in Methanol, 100μg/mL
  • VENLAFAXINE HCL PELLETS 33%
  • Venlafaxine hydrochloride USP/EP/BP
  • Venlafaxine HCl (Wy 45030 HCl)
  • Venlafaxine for system suitability (Y0000588)Q: What is Venlafaxine for system suitability (Y0000588) Q: What is the CAS Number of Venlafaxine for system suitability (Y0000588)
  • Venlafaxine hydrochloride (Y0000587)
  • Venlafaxine HydrochlorideQ: What is Venlafaxine Hydrochloride Q: What is the CAS Number of Venlafaxine Hydrochloride Q: What is the storage condition of Venlafaxine Hydrochloride
  • Venlafaxine Hydrochloride (1711268)
  • Venlift
  • Vexor
  • Venlafaxine hydrochloride, 98%, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI)
  • Venlafaxine (hydrochloride) (CRM)
  • VENLAFAXINE HCL
  • EFFEXOR
  • D,L-VENLAFAXINE
  • D,L-VENLAFAXINE, HYDROCHLORIDE
  • Venlafaxine HCL API
  • Venlafaxine HCl 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
  • Venlafaxine Hydrochloride (non sterile)
  • Venelafaxine Reference Standard
  • Venlafaxine hydrochloride in methanol
  • Venlafaxine hvdrochloride
  • Venlafaxine hydrochloride, Serotonin-norepinephrine reuptake inhibitor
  • Venlafaxine hydrochloride, 10 mM in DMSO
  • VENLAFAXINE HYDROCHLORIDE USP
  • DL-Venlafaxine HCl - Bio-X ?
  • Venlafaxine hydrochloride 100 μg/mL in Acetonitrile
  • Venlafaxine Hydrochloride 1.0 mg/ml in Methanol (as free base)
  • Venlafaxine.HCl, 1mg/ml in Methanol (as free base)
  • Venlafaxine hydrochloride: 1-[(1RS)-2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
  • 99300-78-4
  • 00-00-2
  • 9300-78-4
  • C17H27NO2.HCl
  • C17H27NO2
  • C17H28ClNO2
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