187218-90-2

物理化學(xué)性質(zhì)
沸點(diǎn)684.2±55.0 °C(Predicted)
密度1.238±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)9.08±0.40(Predicted)
應(yīng)用領(lǐng)域
用途一
SRA880 is a non-peptide somatostatin sst(1) receptor antagonist. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0) or a wide range of neurotransmitter receptors, except for the human dopamine D4 receptors. SRA880 positively modulates release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.