| Identification | More | [Name]
2,4-Dichlorobenzyl chloride | [CAS]
94-99-5 | [Synonyms]
2,4-DCBC
2,4-DICHLOROBENZYL CHLORIDE
A 2,4-TRICHLOROTOLUENE
AKOS BBS-00004051
ALPHA,2,4-TRICHLOROTOLUENE
DICHLOROBENZYL-2,4 CHLORIDE
2,4-dichloro-1-(chloromethyl)-benzen
2,4-Dichloro-1-(chloromethyl)benzene
2,4-dichloro-1-chloromethyl-benzene
-2,4-Trichlorotoluene
benzene,2,4-dichloro-1-(chloromethyl)-
Toluene, alpha2,4-trichloro-
toluene,α,2,4-trichloro-
α,2,4-trichlorotoluene
2,4-dichlorobenzylchlorid
à,2,4-trichlorotoluene
2,4,ALPHA-TRICHLOROTOLUENE
2,4-Dichlorbenzylchlorid
2,4-Dichlorobenzoylchloride
7) 2,4-DI CHLORO BENZYL CHLORIDE | [EINECS(EC#)]
202-381-0 | [Molecular Formula]
C7H5Cl3 | [MDL Number]
MFCD00000895 | [Molecular Weight]
195.47 | [MOL File]
94-99-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to very light yellow oily liquid | [Melting point ]
-2.6 °C (lit.) | [Boiling point ]
248 °C (lit.) | [density ]
1.407 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.576(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Oily Liquid | [color ]
Clear colorless to very light yellow | [BRN ]
387220 | [InChI]
InChI=1S/C7H5Cl3/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2 | [InChIKey]
IRSVDHPYXFLLDS-UHFFFAOYSA-N | [SMILES]
C1(CCl)=CC=C(Cl)C=C1Cl | [LogP]
4.08 | [CAS DataBase Reference]
94-99-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 2,4-dichloro-1-(chloromethyl)-(94-99-5) | [EPA Substance Registry System]
94-99-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C,N | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S60:This material and/or its container must be disposed of as hazardous waste . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [F ]
19 | [Hazard Note ]
Corrosive | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29036990 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Chlorine-->2,2'-Azobis(2-methylpropionitrile)-->2,4-Dichlorotoluene-->ALPHA,ALPHA,2,4-TETRACHLOROTOLUENE-->2,4-Dichlorobenzonitrile-->1,3-Bis(chloromethyl)benzene-->2,4-Dichlorobenzoic acid-->2,4-Dichlorobenzyl alcohol-->Dichloromethane-->Phosphorus trichloride | [Preparation Products]
2,4-Dichlorobenzaldehyde-->ALPHA,ALPHA,2,4-TETRACHLOROTOLUENE-->2,4-Dichlorophenylacetonitrile-->Lonidamine-->5-AMino-1-(2,4-dichlorobenzyl)-1H-indazol-3-ol-->1-((2,4-DICHLOROBENZYL)AMINO)PROPAN-2-OL-->N-(2,4-DICHLOROBENZYL)-2-METHOXYETHANAMINE-->1-(4-Chlorophenyl)-2-(2,4-dichlorophenyl)ethanone |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to very light yellow oily liquid | [Uses]
2,4-Dichlorobenzyl chloride is a reagent used in the addition of dichlorobenzene.
| [Synthesis]
GENERAL STEPS: 2,4-dichlorobenzyl alcohol (17.7 g, 0.1 mol), dichloromethane (30 mL), and N,N-dimethylformamide (DMF, 1 mL) were added to a 100 mL round-bottomed flask, followed by the slow dropwise addition of phosphorus trichloride (4.68 g, 0.034 mol). The reaction mixture was heated to reflux temperature (60-80°C) and the reaction lasted for 2-3 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) until the complete disappearance of the raw material. After completion of the reaction, 2,4-dichlorobenzyl chloride (17.99 g, 92% yield) was purified by distillation. | [References]
[1] Patent: CN106117028, 2016, A. Location in patent: Paragraph 0053; 0054; 0055; 0056 |
|
|