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ChemicalBook--->CAS DataBase List--->910482-46-1

910482-46-1

910482-46-1 Structure

910482-46-1 Structure
IdentificationBack Directory
[Name]

CY5.5 NHS ESTER
[CAS]

910482-46-1
[Synonyms]

CY5.5 NHS ESTER
[Molecular Formula]

C45H48KN3O16S4
[MDL Number]

MFCD03846169
[MOL File]

910482-46-1.mol
[Molecular Weight]

1054.22
Chemical PropertiesBack Directory
[solubility ]

易溶于DMSO,DMF等有機(jī)溶劑,極易溶于水
[Appearance]

Dark blue solid
[ex/em]

678/706 nm (PBS buffer)
[ε(extinction coefficient)]

211000 L?mol?1?cm?1
[Φ(quantum yield)]

0.21
Hazard InformationBack Directory
[Description]

Cy5.5 NHS Ester (also sold under sulfo-Cyanine5.5 NHS Ester name) is a bright and photostable near-IR dye that is spectrally similar to Alexa Fluor? 680, DyLight? 680, and IRDye? 680 dye. Cy5.5 NHS Ester is completely water-soluble and often a reagent of choice for labeling antibodies, peptides, and proteins that are sensitive toward organic co-solvents. Cy5.5 conjugates are pH insensitive from pH 4 to pH 10 and produce minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems.The NHS ester (succinimidyl ester) of Cy5.5 is the most popular tool for conjugating this dye to a protein or antibody. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
[Chemical Reactivity]

Primary amine
[Abs/Em Maxima]

675/694 nm
[Extinction Coefficient]

190,000 cm-1M-1
[Spectrally Similar Dyes]

Alexa Fluor? 680, DyLight? 680, IRDye? 680
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