| Identification | More | [Name]
4,6-Dimethoxy-2-(phenoxycarbonyl)aminopyrimidine | [CAS]
89392-03-0 | [Synonyms]
2-((PHENOXYCARBONYL)AMINO)-4,6-DIMETHOXYPYRIMIDINE
4,6-Dimethoxy-2-(phenoxycarbonyl)aminopyrimidine
PHENYL-4,6-DIMETHOXY-2-PYRIMIDYLAMINO FORMATE
4,6-dimethoxy-N-phenyl-2-pyrimidinamine
(4,6-DIMETHOXY-PYRIMIDIN-2-YL)-CARBAMIC ACID PHENYL ESTER
Phenyl(4,6-dimethoxy-2-pyrimidinyl)carbamate
PHENYL-4,6-DIMETHOXY-2-PYERIMIDYLAMINO FORMATE
phenyl N-(4,6-dimethoxypyrimidin-2-yl)carbamate
Carbamic acid, (4,6-dimethoxy-2-pyrimidinyl)-, phenyl ester | [EINECS(EC#)]
406-600-2 | [Molecular Formula]
C13H13N3O4 | [MDL Number]
MFCD02947731 | [Molecular Weight]
275.26 | [MOL File]
89392-03-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,N | [Risk Statements ]
R43:May cause sensitization by skin contact.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S24:Avoid contact with skin .
S37:Wear suitable gloves .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3077 9/PG III | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
2933599590 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Powder | [Uses]
Intermediate for the production of Sulfonyl Urea herbicides. Product Data Sheet | [Flammability and Explosibility]
Nonflammable | [Synthesis]
To a stirred solution of 2-amino-4,6-dimethoxypyrimidine (1 g, 6.45 mmol) in acetonitrile (10 mL) was added triethylamine (0.85 g, 8.40 mmol) at room temperature, followed by the slow dropwise addition of phenyl chloroformate (1.31 g, 8.37 mmol). The reaction mixture was heated to 60 °C and stirred for 6 hours. After completion of the reaction, the mixture was cooled to room temperature, diluted with water (6 mL), the precipitated solid was collected by filtration and dried under vacuum to afford 2-((phenoxycarbonyl)aminomethyl)-4,6-dimethoxypyrimidine (Compound 6) as a white solid in the following yields: 1.48 g, 83%; melting point: 119 °C; 1H NMR (400 MHz, DMSO-d6): δ 7.65 (s 1H), 7.42-7.40 (m, 2H), 7.18-7.14 (m, 3H), 5.80 (s, 1H), 3.96 (s, 6H); ESI-MS: m/z, 276.1 (M + 1). | [References]
[1] Asian Journal of Chemistry, 2017, vol. 29, # 7, p. 1477 - 1481 |
|
|