| Identification | More | [Name]
DIMETHYL 2,6-NAPHTHALENEDICARBOXYLATE | [CAS]
840-65-3 | [Synonyms]
2,6-NAPHTHALENEDICARBOXYLIC ACID DIMETHYL ESTER
2,6-NAPHTHALIC ACID DIMETHYL ESTER
DIMETHYL 2,6-NAPHTHALENEDICARBOXYLATE
DIMETHYL NAPHTHALENE-2,6-DICARBOXYLATE
NAPHTHALENE-2,6-DICARBOXYLIC ACID DIMETHYL ESTER
TIMTEC-BB SBB007910
2,6-Dicarbomethoxynaphthalene
Dimethyl ester of 2,6-naphthalenedicarboxylic acid
dimethyl2,6-naphthalate
NDC
Dimethyl-2,6-naphthalene dicaboxylate
ndcm
DIMETHYL 2,6-NAPHTHALENEDICARBOXYLATE, 9 8%
2,6-NAPHTHALENEDICARBOXYLIC ACID DIMETHYL ESTER 99+%
2,6-NAPTHALENE DI-CARBOXYLIC ACID DIMETHYL ESTER
Dimethyl naphthalene-2,6-dicarboxylate, 99+% | [EINECS(EC#)]
212-661-4 | [Molecular Formula]
C14H12O4 | [MDL Number]
MFCD00004100 | [Molecular Weight]
244.24 | [MOL File]
840-65-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
187-193 °C(lit.)
| [Boiling point ]
347.16°C (rough estimate) | [density ]
1.2379 (rough estimate) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.5389 (estimate) | [Fp ]
232°C | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [color ]
White to Almost white | [Water Solubility ]
Soluble in hot toluene (very faint turbidity). Insoluble in water. | [BRN ]
987259 | [InChI]
InChI=1S/C14H12O4/c1-17-13(15)11-5-3-10-8-12(14(16)18-2)6-4-9(10)7-11/h3-8H,1-2H3 | [InChIKey]
GYUVMLBYMPKZAZ-UHFFFAOYSA-N | [SMILES]
C1=C2C(C=C(C(OC)=O)C=C2)=CC=C1C(OC)=O | [LogP]
3.5 at 25℃ | [CAS DataBase Reference]
840-65-3(CAS DataBase Reference) | [EPA Substance Registry System]
Dimethyl 2,6-naphthalenedicarboxylate (840-65-3) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
2917.39.7000 |
| Hazard Information | Back Directory | [Uses]
Dimethyl naphthalene-2,6-dicarboxylate is used as a pharmaceutical intermediate. | [Flammability and Explosibility]
Nonflammable | [Synthesis]
To a round bottom flask was added 20 g of 2,6-naphthalenedicarboxylic acid dissolved in 150 mL of methanol and 15 mL of concentrated sulfuric acid was added as a catalyst. The reaction mixture was heated to reflux for 24 hours to complete the esterification reaction. Upon completion of the reaction, the mixture was slowly poured into 500 mL of ice water to quench the reaction. The resulting white precipitate was collected by diafiltration and washed with plenty of water to remove residual acid and methanol. Finally, the product was dried in a vacuum drying oven to give 20 g of dimethyl 2,6-naphthalenedicarboxylate in 89% yield. | [References]
[1] Patent: CN103864711, 2016, B. Location in patent: Paragraph 0102; 0103; 0104
[2] RSC Advances, 2014, vol. 4, # 35, p. 18100 - 18107 |
|
|