| Identification | Back Directory | [Name]
BDP FL maleimide | [CAS]
773859-49-7 | [Synonyms]
BDP FL maleimide
BDP FL maleimide/MAL
OEMKXDGSMCHMJQ-UHFFFAOYSA-N | [Molecular Formula]
C20H21BF2N4O3 | [MDL Number]
MFCD28385513 | [MOL File]
773859-49-7.mol | [Molecular Weight]
414.21 |
| Chemical Properties | Back Directory | [solubility ]
Soluble in DMSO, DMF, DCM | [InChI]
InChI=1S/C20H21BF2N4O3/c1-13-11-14(2)26-17(13)12-16-4-3-15(27(16)21(26,22)23)5-6-18(28)24-9-10-25-19(29)7-8-20(25)30/h3-4,7-8,11-12H,5-6,9-10H2,1-2H3,(H,24,28) | [InChIKey]
OEMKXDGSMCHMJQ-UHFFFAOYSA-N | [SMILES]
C(C1=CC=C2C=C3C(=CC(=[N]3[B+3]([N-]21)([F-])[F-])C)C)CC(=O)NCCN1C(C=CC1=O)=O |
| Hazard Information | Back Directory | [Description]
BDP FL maleimide is a BDP FL linker containing a maleimide group, which selectively reacts with free thiol, sulfhydryl, or mercapto group via Michael addition to form a stable carbon sulfur bond.
BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, peptide modification, and can replace fluorescein for microscopy. | [Uses]
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy[1]. | [References]
[1] Jakob W Buecheler, et al. Impact of Payload Hydrophobicity on the Stability of Antibody-Drug Conjugates. Mol Pharm. 2018 Jul 2;15(7):2656-2664. DOI:10.1021/acs.molpharmaceut.8b00177 |
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Alfa Chemistry
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1-516-6625404 |
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https://www.alfa-chemistry.com |
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