| Identification | More | [Name]
3-Thienylmethanol | [CAS]
71637-34-8 | [Synonyms]
3-HYDROXYMETHYLTHIOPHENE
3-THIENYLMETHANOL
3-THIOPHENEMETHANOL
RARECHEM AL BD 0549
THIOPHENE-3-METHANOL
TIMTEC-BB SBB004309
3-Thiophene
3-THIOPHENEMETHANOL 98+%
THIOPHENE-3-YL METHANOL | [EINECS(EC#)]
275-741-8 | [Molecular Formula]
C5H6OS | [MDL Number]
MFCD00014534 | [Molecular Weight]
114.17 | [MOL File]
71637-34-8.mol |
| Chemical Properties | Back Directory | [Boiling point ]
86-88 °C/10 mmHg (lit.) | [density ]
1.211 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.564(lit.)
| [Fp ]
213 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
clear liquid | [pka]
14.49±0.10(Predicted) | [color ]
Colorless to Almost colorless | [Water Solubility ]
Slightly soluble in water. | [Detection Methods]
HPLC | [BRN ]
106460 | [InChI]
InChI=1S/C5H6OS/c6-3-5-1-2-7-4-5/h1-2,4,6H,3H2 | [InChIKey]
BOWIFWCBNWWZOG-UHFFFAOYSA-N | [SMILES]
C1SC=CC=1CO | [CAS DataBase Reference]
71637-34-8(CAS DataBase Reference) | [NIST Chemistry Reference]
3-Thiophenemethanol(71637-34-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
3-Thiophenemethanol was used in the preparation of 3-substituted thiophene conducting copolymers which has potential applications in electrochromic displays. It was also used in the synthesis of 4-(thiophene-3-ylmethoxy)phthalonitrile. | [Definition]
ChEBI: 3-Thiophenemethanol is a heteroarene. | [General Description]
Comparision of electrochemical polymerization properties of 3-thiophenemethanol and 3-methylthiophene has been reported. | [Synthesis]
The general procedure for the synthesis of 3-thiophene methanol from 3-bromothiophene-4-carboxaldehyde was as follows: 3-bromothiophene-4-carboxaldehyde (930 mg, 5.0 mmol), sodium acetate (820 mg, 10.0 mmol), methanol (30 mL), and palladium chloride (45 mg) were mixed in a balloon-covered glass vial filled with hydrogen. The reaction mixture was stirred at 35 °C for 4 h before being filtered and washed with methanol. Subsequently, the solvent was removed by reduced pressure distillation and the residue was dissolved in water, neutralized with solid sodium bicarbonate and extracted with ethyl acetate. The organic phase was dried with anhydrous sodium sulfate and filtered. Finally, the solvent was removed by reduced pressure distillation and the residue was purified by column chromatography to give 3-thiophene methanol (428 mg, 78% yield). | [References]
[1] Tetrahedron Letters, 2012, vol. 53, # 29, p. 3798 - 3801 |
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