| Identification | More | [Name]
N'-Nitro-D-arginine | [CAS]
66036-77-9 | [Synonyms]
D-ARGININE(NO2)-OH
D-NNA
D-NOARG
H-D-ARG(NO2)-OH
H-G-NITRO-D-ARGININE
NG-NITRO-D-ARGININE
NITRO-D-ARGININE
N-OMEGA-NITRO-D-ARGININE
R(-)-N5-[IMINO(NITROAMINO)METHYL]-ORNITHINE
D-Arg(NO2)-OH
N-NITROAMIDINO-D-ORNITHINE
N-ω-Nitro-D-arginine
NG-NITRO-D-ARGININE (D-NOARG, D-NNA) R(-)-N5-(IMINO(NITROA
N5-Nitro-D-arginine
D-NARG | [EINECS(EC#)]
200-528-9 | [Molecular Formula]
C6H13N5O4 | [MDL Number]
MFCD00066013 | [Molecular Weight]
219.2 | [MOL File]
66036-77-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
253-254 °C(Solv: water (7732-18-5)) | [Boiling point ]
422.3±55.0 °C(Predicted) | [density ]
1.65±0.1 g/cm3(Predicted) | [storage temp. ]
Store at RT. | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
2.49±0.24(Predicted) | [color ]
White to off-white | [CAS DataBase Reference]
66036-77-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections. N'-Nitro-D-arginine also inhibits neutrophil migration by blocking receptors for tumour necrosis factor alpha (TNFα) and interleukin 8 (IL8)[1]. | [in vivo]
N'-Nitro-D-arginine (40 mg/kg) produces a significant increase in systolic blood pressure in the chronic, awake, instrumented sheep model[1]. | [References]
[1] C K Narkowicz, et al. Delayed recovery from NG-nitro-L-arginine in the conscious sheep. Clin Exp Pharmacol Physiol. 1991 Dec;18(12):843-6. DOI:10.1111/j.1440-1681.1991.tb01404.x |
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