Identification | Back Directory | [Name]
HOMATROPINE HYDROCHLORIDE | [CAS]
637-21-8 | [Synonyms]
homatropineHCl Homatropinhydrochlorid HOMATROPINE HYDROCHLORIDE (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate hydrochloride (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-ethanoate hydrochloride 2-hydroxy-2-phenyl-acetic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride | [EINECS(EC#)]
211-280-0 | [Molecular Formula]
C16H22ClNO3 | [MDL Number]
MFCD00050613 | [MOL File]
637-21-8.mol | [Molecular Weight]
311.8 |
Chemical Properties | Back Directory | [Melting point ]
226 °C | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Merck ]
14,4730 | [CAS DataBase Reference]
637-21-8 |
Hazard Information | Back Directory | [Uses]
Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1]. | [References]
[1] Gore A, et al. Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats. Toxicol Sci. 2012 Apr;126(2):515-24. DOI:10.1093/toxsci/kfs009 |
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