Identification | Back Directory | [Name]
(R)-1-methoxypropan-2-amine hydrochloride | [CAS]
626220-76-6 | [Synonyms]
CAS:626220-76-6 (R)-1-Methoxypropan-2-amine, HCl (R)-(-)-1-Methoxy-2-PropylaMine HCl (R)-1-methoxypropan-2-amine hydrochloride (2R)-1-Methoxypropan-2-amine hydrochloride (R)-(-)-1-Methoxy-2-propylaMine hydrochloride 2-PropanaMine, 1-Methoxy-, hydrochloride, (2R)- ((R)-2-Methoxy-1-methylethyl)amine hydrochloride | [Molecular Formula]
C4H12ClNO | [MDL Number]
MFCD12405301 | [MOL File]
626220-76-6.mol | [Molecular Weight]
126 |
Chemical Properties | Back Directory | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [Appearance]
White to off-white Solid | [Optical Rotation]
Consistent with structure |
Hazard Information | Back Directory | [Synthesis]
Step 3: (S)-Boc-2-methoxy-1-methylethylamine (955399-15-2) was dissolved in methanol (40 mL) and 3M hydrochloric acid solution (10 mL) was slowly added. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was co-evaporated with ethanol (20 mL) to afford (S)-2-methoxy-1-methylethylamine hydrochloride as a light brown oil (1.42 g, 100% yield). Mass spectrometry analysis showed the molecular ion peak (M+H)+ m/z = 90. | [References]
[1] Patent: US2008/4442, 2008, A1. Location in patent: Page/Page column 197 [2] Patent: WO2008/55840, 2008, A1. Location in patent: Page/Page column 58 [3] Patent: US2009/163502, 2009, A1. Location in patent: Page/Page column 40 [4] Patent: US2009/163499, 2009, A1. Location in patent: Page/Page column 28 [5] Patent: US2010/324056, 2010, A1. Location in patent: Page/Page column 30 |
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