| Identification | More | [Name]
4-HYDROXYCARBAZOLE | [CAS]
54989-33-2 | [Synonyms]
4 HYDROXY 9(H)CARBAZOLE
4-HYDROXYCARBAZOLE
9H-CARBAZOL-4-OL
4-hydroxy carbonzole
4-hydroxy-9-(H)-Carbazol] | [EINECS(EC#)]
258-034-9 | [Molecular Formula]
C12H9NO | [MDL Number]
MFCD02178385 | [Molecular Weight]
183.21 | [MOL File]
54989-33-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
169-173 °C(lit.)
| [Boiling point ]
406.0±28.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [pka]
13.43±0.58(Predicted) | [InChI]
InChI=1S/C12H9NO/c14-13-11-7-3-1-5-9(11)10-6-2-4-8-12(10)13/h1-8,14H | [InChIKey]
PWERSDAXNCUOIB-UHFFFAOYSA-N | [SMILES]
N1(O)C2=C(C=CC=C2)C2=C1C=CC=C2 | [CAS DataBase Reference]
54989-33-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT |
| Hazard Information | Back Directory | [Uses]
9H-Carbazol-9-ol is a minor product converted from 9H-carbazole. 9H-Carbazole and its derivatives are of special pharmaceutical interest due to their versatile biological activities.
9H-Carbazole itself was found to be an inhibitor of
angiogenesis and inflammation.
Furthermore, 9H-carbazole is a basic structural element of
a variety of naturally active and synthetic compounds with
a broad range of action, showing antibacterial, antifungal, antiparasitic
, antiviral,
anticancer, adrenoceptor blocking
, or protein-kinase inhibition activities[1]. | [References]
[1] DOREEN WALDAU. Characterization of new oxidation products of 9H-carbazole and structure related compounds by biphenyl-utilizing bacteria[J]. Applied Microbiology and Biotechnology, 2009, 81 6: 1023-1031. DOI:10.1007/s00253-008-1723-8. |
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