| Identification | More | [Name]
4-Bromophenylboronic acid | [CAS]
5467-74-3 | [Synonyms]
4-BROMOBENZENEBORONIC ACID
4-BROMOBENZENEBORONIC ACID/ANHYDRIDE
4-BROMOPHENYLBORIC ACID ANHYDRIDE
4-BROMOPHENYLBORONIC ACID
AKOS BRN-0005
P-BROMO BENZENE BORONIC ACID
P-BROMOPHENYLBORONIC ACID
RARECHEM AH PB 0075
(4-bromophenyl)-boronicaci
p-bromo-benzeneboronicaci
p-bromophenylboricacid
dihydroxy-4-bromophenylborane
4-Bromobenzeneboronicacid,97+%
4-Bromophenylboronic
Boronic acid, (4-bromophenyl)-
4-bromophenylboric acid
4-Bromobenzeneboronic acid4-Bromobenzeneboronic acid
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
(4-Bromophenyl)boranediol
(4-Bromophenyl)boranic acid | [EINECS(EC#)]
226-779-9 | [Molecular Formula]
C6H6BBrO2 | [MDL Number]
MFCD00002104 | [Molecular Weight]
200.83 | [MOL File]
5467-74-3.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
284-288 °C (lit.) | [Boiling point ]
315.0±44.0 °C(Predicted) | [density ]
1.67±0.1 g/cm3(Predicted) | [storage temp. ]
0-6°C | [form ]
Crystalline Powder | [pka]
8.32±0.10(Predicted) | [color ]
Off-white to light beige | [Water Solubility ]
Soluble in methanol. Insoluble in water. | [BRN ]
2936347 | [InChI]
InChI=1S/C6H6BBrO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H | [InChIKey]
QBLFZIBJXUQVRF-UHFFFAOYSA-N | [SMILES]
B(C1=CC=C(Br)C=C1)(O)O | [CAS DataBase Reference]
5467-74-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
CY8650000
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29319099 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
suzuki reaction | [Synthesis]
GENERAL METHOD: 4-Bromoaniline (0.5 mmol, 1.0 eq.) was dissolved in methanol (1.0 mL), hydrochloric acid (0.5 mL, 1.5 mmol, 3.0 eq.) and water (0.5 mL) were added. The reaction mixture was stirred for 2 min and then sodium nitrite solution (0.25 mL, prepared by dissolving 35 mg of sodium nitrite in 0.25 mL of water) was added. Stir at 0-5 °C for 30 min, followed by the addition of hydrochloric acid (135 mg, 1.5 mmol, 3.0 equiv) in methanol (1.0 mL). Stirring was continued for 60 min. After completion of the reaction, it was diluted with water (10 mL) and extracted with dichloromethane (50 mL, 3 times). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 4-bromophenylboronic acid. | [References]
[1] Synlett, 2014, vol. 25, # 11, p. 1577 - 1584
[2] Chemistry - A European Journal, 2014, vol. 20, # 22, p. 6608 - 6612 |
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