| Identification | More | [Name]
2-PROPIONYLTHIAZOLE | [CAS]
43039-98-1 | [Synonyms]
2-PROPIONYLTHIAZOLE
ETHYL 2-THIAZOLYL KETONE
FEMA NUMBER 3611
1-(2-thiazolyl)-1-propanon
2-propionylthiazol
2-propionyl-thiazol
2-thiazolyl-1-propanone
Thiazole, 2-(1-oxopropyl)
Thiazole, 2-propionyl-
2-Propionylthiazole,99%
1-Propanone, 1-(2-thiazolyl)-
2-Propionyll thiazole | [Molecular Formula]
C6H7NOS | [MDL Number]
MFCD01681404 | [Molecular Weight]
141.19 | [MOL File]
43039-98-1.mol |
| Chemical Properties | Back Directory | [Boiling point ]
110°C/5mm | [density ]
1.174 | [FEMA ]
3611 | [refractive index ]
1.5350-1.5390 | [Fp ]
110°C/5mm | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
clear liquid | [pka]
-0.03±0.10(Predicted) | [color ]
Colorless to Light yellow to Light orange | [Odor]
at 0.10 % in dipropylene glycol. cereal bread nutty popcorn | [Odor Type]
bready | [Water Solubility ]
Not miscible or difficult to mix with water. | [JECFA Number]
1042 | [LogP]
0.90 | [CAS DataBase Reference]
43039-98-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
1993 | [RTECS ]
XJ5123000 | [HazardClass ]
IRRITANT | [HS Code ]
2934100090 |
| Hazard Information | Back Directory | [Occurrence]
Reported found in lard. | [Uses]
Used as flavoring agent and fragrance chemical compounds. | [Synthesis]
GENERAL PROCEDURE: A flame-dried and cooled round-bottomed flask under nitrogen protection was charged with allyl alcohol 51 (0.5 mmol) and tetrahydrofuran (THF, 2.5 mL). The reaction mixture was stirred at 0 °C for 5 min before a one-time addition of sodium hydride (NaH, 1 mmol, 2 equiv.), followed by a slow warming of the mixture to room temperature. Upon completion of the reaction, the reaction was quenched by the addition of saturated ammonium chloride (NH4Cl, 2 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 10 mL × 2) and the combined organic phases were washed with saturated saline (15 mL). The organic layer was dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to remove the solvent, and the residue was purified by silica gel column chromatography to give the target ketone product 52. | [References]
[1] Tetrahedron, 2011, vol. 67, # 19, p. 3406 - 3411 |
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