| Identification | More | [Name]
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE | [CAS]
3171-45-7 | [Synonyms]
1,2-DIMETHYL-4,5-DIAMINOBENZENE
2-AMINO-4,5-DIMETHYLANILINE
2-AMINO-4,5-DIMETHYLPHENYLAMINE
4,5-DIAMINO-1,2-DIMETHYLBENZENE
4,5-DIAMINO-O-XYLENE
4,5-DIMETHYL-1,2-PHENYLENEDIAMINE
4,5-DIMETHYL-BENZENE-1,2-DIAMINE
4,5-DIMETHYL-O-PHENYLENE DIAMINE
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE
1,2-Benzenediamine, 4,5-dimethyl-
4,5-Dimethyl-1,2-benzenediamine
4,5-dimethyl-2-benzenediamine
4,5-DIMETHYL-1,2-PHENYLENEDIAMINE 95+%
1,2-DIAMINO-4,5-DIMETHYLBENZENE | [EINECS(EC#)]
221-635-1 | [Molecular Formula]
C8H12N2 | [MDL Number]
MFCD00972722 | [Molecular Weight]
136.19 | [MOL File]
3171-45-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
127-129 °C (lit.) | [Boiling point ]
279.6±35.0 °C(Predicted) | [density ]
1.076±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Crystalline Mass, Crystals or Chunks | [pka]
5.02±0.10(Predicted) | [color ]
White to yellow to brownish | [Water Solubility ]
Slightly soluble in water. | [Sensitive ]
Air & Light Sensitive | [InChI]
InChI=1S/C8H12N2/c1-5-3-7(9)8(10)4-6(5)2/h3-4H,9-10H2,1-2H3 | [InChIKey]
XSZYBMMYQCYIPC-UHFFFAOYSA-N | [SMILES]
C1(N)=CC(C)=C(C)C=C1N | [CAS DataBase Reference]
3171-45-7(CAS DataBase Reference) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
1,2-Benzenediamine, 4,5-dimethyl- (3171-45-7) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
6.1(a) | [PackingGroup ]
II | [HS Code ]
29212900 |
| Hazard Information | Back Directory | [Chemical Properties]
White to light brown solid | [Uses]
4, 5-dimethyl-o-phenylenediamine used in the determination of aromatic aldehydes by high performance liquid chromatography after precolumn fluorescent derivatization. For the determination of vanillin. | [Uses]
Employed in the preparation of transition metal complexes1 and quinoxalinones.2 | [Synthesis Reference(s)]
Tetrahedron Letters, 42, p. 2277, 2001 DOI: 10.1016/S0040-4039(01)00163-0 | [Synthesis]
(4.1) The reducing system was prepared by adding 32 mL of deionized water to 72 mL of anhydrous ethanol solution containing 12.9 g (57.17 mmol; 9.5 eq.) of SnCl2-2H2O. Subsequently, 1 g (6.02 mmol; 1 eq.) of 4,5-dimethyl-2-nitroaniline was added in batches at room temperature and under inert atmosphere. The reaction mixture was heated to reflux for 1 h. The reaction process was monitored by thin layer chromatography (TLC) (unfolding agent: ethyl acetate). After completion of the reaction, it was cooled to room temperature and the reaction mixture was poured into 120 mL of water and neutralized with NaHCO3. The tin salts and NaHCO3 were removed by filtration through filter paper. the filtrate was extracted with dichloromethane (organic phase 1) and the residual solid was continuously extracted with dichloromethane through a Soxhlet extractor for 2 days. The dichloromethane phase after Soxhlet extraction was washed once with water (organic phase 2). Organic phases 1 and 2 were combined, dried over anhydrous MgSO4, filtered and concentrated. The crude product was purified by silica gel fast column chromatography (elution gradient: cyclohexane/ethyl acetate 2/8; pure ethyl acetate; ethyl acetate/methanol 95/5). The resulting target compound (No. cs 357-1) was an orange solid in quantitative yield. rf = 0.33 (ethyl acetate). 1H NMR (CDCl3, ppm): 2.12 (s, 6H, 2 x CH3); 6.52 (s, 2H, 2 x aromatic CH). 13C NMR (CDCl3, ppm): 18.99 (CH3); 118.64 (aromatic CH); 128.02 (quaternary carbon-CH3); 132.38 (quaternary carbon-N). Mass spectrum (MS): [M + H]+ m/z = 137.1; [M + Na]+ m/z = 159.1; [M + K]+ m/z = 175.2. | [References]
[1] Patent: WO2011/117830, 2011, A1. Location in patent: Page/Page column 20
[2] Chemistry - A European Journal, 2018, vol. 24, # 36, p. 8989 - 8993
[3] ChemCatChem, 2016, vol. 8, # 15, p. 2461 - 2465
[4] Biochemische Zeitschrift, 1956, vol. 327, p. 422,447
[5] Chemische Berichte, 1901, vol. 34, p. 2255 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE(3171-45-7)MS
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE(3171-45-7)1HNMR
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE(3171-45-7)13CNMR
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE(3171-45-7)IR1
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE(3171-45-7)IR2
4,6-DIMETHYL-1,2-PHENYLENEDIAMINE(3171-45-7)Raman
|
|
|