| Identification | Back Directory | [Name]
4-(4-METHOXYPHENOXY)ANILINE | [CAS]
31465-36-8 | [Synonyms]
AKOS 91179
AKOS B021930
CHEMBRDG-BB 4008768
ART-CHEM-BB B021930
SALOR-INT L300853-1EA
4-(4-METHOXYPHENOXY)ANILINE
4-(4-METHOXYPHENOXY)BENZENAMINE
4-(4-Methoxyphenoxy)aniline 98+%
Benzenamine, 4-(4-methoxyphenoxy)-
4-(4-methoxyphenoxy)aniline(SALTDATA: FREE)
JR-8692, 4-(4-Methoxyphenoxy)benzenamine, 97%
4-(4-Aminophenoxy)anisole, 4-Amino-4'-methoxydiphenyl ether | [EINECS(EC#)]
250-644-3 | [Molecular Formula]
C13H13NO2 | [MDL Number]
MFCD00044105 | [MOL File]
31465-36-8.mol | [Molecular Weight]
215.25 |
| Chemical Properties | Back Directory | [Melting point ]
79 °C | [Boiling point ]
359.6±27.0 °C(Predicted) | [density ]
1.155±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
powder | [pka]
4.93±0.10(Predicted) | [color ]
Charcoal |
| Hazard Information | Back Directory | [Synthesis]
Step 2. Synthesis of 4-(4-methoxyphenoxy)aniline
To a solution of 1-methoxy-4-(4-nitrophenoxy)benzene (12.0 g, 49 mmol) in ethyl acetate (EtOAc, 250 mL) was added 5% Pt/C catalyst (1.5 g). The resulting suspension was reacted by shaking under hydrogen atmosphere (50 psi) for 18 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth (Celite) pad to remove the catalyst. The filtrate was concentrated under reduced pressure to give an oily product, which gradually solidified on standing (10.6 g, 100% yield). The product was characterized by 1H-NMR (CDCl3): δ 3.54 (broad single peak, 2H), 3.78 (single peak, 3H), 6.65 (double peak, J = 8.8 Hz, 2H), 6.79-6.92 (multiple peaks, 6H); EI-MS m/z 215 (M+). | [References]
[1] Patent: US2008/269265, 2008, A1. Location in patent: Page/Page column 14
[2] Patent: EP1449834, 2004, A2. Location in patent: Page 22
[3] Patent: EP1042305, 2005, B1. Location in patent: Page/Page column 27
[4] Patent: US2007/244120, 2007, A1. Location in patent: Page/Page column 17
[5] Patent: US2003/207914, 2003, A1. Location in patent: Page/Page column 8 |
|
|