| Identification | More | [Name]
3-Amino-4-phenylbutyric acid hydrochloride | [CAS]
3060-41-1 | [Synonyms]
3-Amino-4-phenylbutyric acid hydrochloride
4-AMINO-3-PHENYLBUTIRIC ACID
4-AMINO-3-PHENYL-BUTYRIC ACID
FENIBUT
PHENIBUT
TIMTEC-BB SBB001567
3-AMINO-4-PHENYLBUTYRIC ACID HCL
Phenibut(4-Amino-3-Phenylbutanoic Acid HCl) | [EINECS(EC#)]
214-079-6 | [Molecular Formula]
C10H14ClNO2 | [MDL Number]
MFCD00456233 | [Molecular Weight]
215.68 | [MOL File]
3060-41-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
194-201°C | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [InChI]
InChI=1S/C10H13NO2.ClH/c11-7-9(6-10(12)13)8-4-2-1-3-5-8;/h1-5,9H,6-7,11H2,(H,12,13);1H | [InChIKey]
XSYRYMGYPBGOPS-UHFFFAOYSA-N | [SMILES]
C(C1C=CC=CC=1)(CN)CC(=O)O.Cl | [CAS DataBase Reference]
3060-41-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Phenibut is a derivative of γ-Aminobutyric Acid (A602920); an important inhibitory neurotransmitter. Phenibut possesses neuroprotective activity. | [General Description]
4-Amino-3-phenyl-butyric acid hydrochloride is a derivative of γ-Aminobutyric Acid which possesses neuroprotective activity. It is an organic compound characterized by the presence of both a carboxylic acid and an amine group. It′s an amino acid and holds substantial importance in the fields of biochemistry and physiology. Its versatile nature allows for a broad spectrum of applications in scientific research, particularly in studies involving enzyme inhibition and receptor activation. | [Synthesis]
GENERAL METHOD: 4-phenyl-2-pyrrolidone (0.4 mmol) and 10 mL of HCl (6.0 mol/L) were added to a round bottom flask. The reaction mixture was magnetically stirred under reflux conditions for 12 hours. After completion of the reaction, the solvent was removed by evaporation under reduced pressure to give 3-phenyl-4-aminobutyric acid hydrochloride. | [References]
[1] New Journal of Chemistry, 2015, vol. 39, # 3, p. 1643 - 1653
[2] Journal of the Brazilian Chemical Society, 2017, vol. 28, # 2, p. 285 - 298
[3] RSC Advances, 2014, vol. 4, # 5, p. 2538 - 2545 |
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